Acute traumatic dislocation without fractures of the thumb carpometacarpal (CMC) joint is extremely rare in children. Treatment options, such as closed reduction with casting or pinning and open reduction with primary ligament repair, remain controversial. Here, we report the first case of an 11-year-old boy with recurrent left thumb CMC joint dislocation due to idiopathic generalized hyperjoint laxity, even after primary open reduction with capsular ligament repair of the thumb CMC joint, eventually treated with Eaton-Littler's ligament reconstruction. Intraoperatively, a drill hole was made in the base of the first metacarpal bone while carefully preventing growth plate injury. Primary ligament reconstruction of the thumb CMC joint may be considered in pediatric cases with systemic hyperjoint laxity or recurrent thumb CMC joint dislocation. In such cases, Eaton-Littler's ligament reconstruction is recommended for thumb CMC joint stability because two prime stabilizers of the dorsoradial ligament and the volar anterior oblique ligament (AOL) are appropriately reconstructed by a half-slip of the flexor carpi radialis tendon.
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http://dx.doi.org/10.7759/cureus.65365 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
This joint practice guideline/procedure standard was collaboratively developed by the European Association of Nuclear Medicine (EANM), the Society of Nuclear Medicine and Molecular Imaging (SNMMI), the European Association of Neuro-Oncology (EANO), and the PET task force of the Response Assessment in Neurooncology Working Group (PET/RANO). Brain metastases are the most common malignant central nervous system (CNS) tumors. PET imaging with radiolabeled amino acids and to lesser extent [F]FDG has gained considerable importance in the assessment of brain metastases, especially for the differential diagnosis between recurrent metastases and treatment-related changes which remains a limitation using conventional MRI.
View Article and Find Full Text PDFNat Cancer
January 2025
Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
The coronavirus disease 2019 pandemic substantially impacted the delivery of cancer services and programs. Here we reviewed and synthesized the global scale and impact of pandemic-related delays and disruptions on cancer services, including diagnosis, diagnostic procedures, screening, treatment and supportive and palliative care. Based on data from 245 articles in 46 countries, we observed declines in the number of cancer screening participation (39.
View Article and Find Full Text PDFOsteoarthritis Cartilage
December 2024
Rheumatology, Department of Musculoskeletal Medicine, University Hospital Lausanne and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland. Electronic address:
Objective: Bone marrow adipose tissue (BMAT) is emerging as an important regulator of bone formation and energy metabolism. Lipolysis of BMAT releases glycerol and fatty acid substrates that are catabolized by osteoblasts. Here, we investigated whether BMAT lipolysis is involved in subchondral bone formation in hand osteoarthritis (OA).
View Article and Find Full Text PDFGeorgian Med News
October 2024
Worthing Hospital, University Hospitals Sussex NHS Foundation Trust, United Kingdom.
Background: Bennett's fracture, a fracture-dislocation of the base of the first metacarpal, poses significant challenges due to the unique biomechanics of the thumb's carpometacarpal (CMC) joint. Effective management is critical to restoring thumb function and preventing long-term complications such as arthritis and instability.
Objective: This article provides a comprehensive overview of Bennett's fracture, including its mechanism of injury, diagnostic considerations, and management strategies, with a focus on conservative and surgical options.
Biomater Adv
December 2024
National and Local Joint Engineering Laboratory for Synthetic Technology of High Performance Polymer, College of Chemistry, Jilin University, Changchun 130012, China. Electronic address:
On account of the existence of antibiotic resistance, the wound healing of pathogenic infection is still a challenge in modern society. A desirable wound dressing should own the abilities of adhesiveness, hemostasis and good mechanical property, meanwhile the property of eliminating bacteria without side effects is also highly needed. In this work, we established a kind of hydrogel based on carboxymethyl cellulose-graft-tyramine (CMC-Ty) and MXene (TiCT) through employing HO/HRP (horseradish peroxidase) as the initiator, then the as-prepared hydrogel (named CMC-Ty/MXene) was immersed in tannic acid (TA) solution, and this TA-treated hydrogel was called CMC-Ty/MXene+TA.
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