AI Article Synopsis
- This text discusses how activating chemical bonds at less negative voltages can enhance functional group tolerance and selectivity in organic electrosynthesis.
- Researchers developed a method that combines electro-reduction with hydrogen bonding to make chemical reactions more efficient.
- A specific example showed that they could improve the reduction potential of a compound and perform a complex reaction without needing extra radical sources or prep steps, using a special ionic liquid for the process.
Article Abstract
The reductive activation of chemical bonds at less negative potentials provides a foundation for high functional group tolerance and selectivity, and it is one of the central topics in organic electrosynthesis. Along this line, we report the design of a dual-activation mode by merging electro-reduction with hydrogen bonding activation. As a proof of principle, the reduction potential of -phenylpropiolamide was shifted positively by 218 mV. Enabled by this strategy, the radical Smiles rearrangement of -arylpropiolamides without external radical precursors and prefunctionalization steps was accomplished. [DBU][HOAc], a readily accessible ionic liquid, was exploited for the first time both as a hydrogen bonding donor and as a supporting electrolyte.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339951 | PMC |
| http://dx.doi.org/10.1039/d4sc02821j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Poly[di-aqua-[μ-1,4-bis-(pyridin-3-ylmeth-yl)piperazine][μ-4-(2-carboxyl-atoeth-yl)benzoato]cobalt(II)].
IUCrdata
December 2024
E-35 Holmes Hall, Michigan State University, Lyman Briggs College, 919 E. Shaw Lane, East Lansing, MI 48825, USA.
A layered cobalt coordination polymer containing both 4-(2-carboxyl-atoeth-yl)benzoate (ceb) and 1,4-bis-(3-pyridyl-meth-yl)piperazine (3-bpmp) ligands, [Co(CHO)(CHN)(HO)] or [Co(ceb)(3-bpmp)(HO)] , was isolated and structurally characterized by single-crystal X-ray diffraction. Chain-like [Co(ceb)(HO)] units are oriented parallel to [101]. These are connected into (4,4)-grid coordination polymer layers by tethering 3-bpmp ligands.
View Article and Find Full Text PDFBinary solvent participation in crystals of a multi-aromatic 1,2,3-triazole.
Acta Crystallogr E Crystallogr Commun
January 2025
Oligometrics, Inc., 2510 47th Street, Suite 208, Boulder, CO, 80301, USA.
The X-ray crystal structure of a multi-aromatic substituted 1,2,3-triazole is presented, which shows an extensive three-dimensional hydrogen-bonding network involving two water mol-ecules and two aceto-nitrile mol-ecules. The structure of 4-{[(4-{[1-({[(3,4-di-meth-oxy-phen-yl)meth-yl](3-acetamido-phen-yl)carbamo-yl}meth-yl)-1-1,2,3-triazol-4-yl]meth-oxy}-3-meth-oxy-phen-yl)meth-yl]amino}-benzoic acid-aceto-nitrile-water (1/2/2), CHNO·2CHN·2HO, features amine-linked aromatic groups that have a variety functionality including a carb-oxy-lic acid, an acetamido group, and meth-oxy ethers. All -H groups, and seven out of ten heteroatoms with available lone-pair electrons, participate in hydrogen bonding, with the aid of dimer-bridging water mol-ecules and aceto-nitrile mol-ecules whose methyl groups form close contacts with oxygen atoms.
View Article and Find Full Text PDFCrystal structure of di-μ-acetato-κ :-bis{(acetato-κ ,')tetra-aqua-[1-(pyridin-2-yl-methylidene-κ)-2-(pyridin-2-yl-κ)hydrazine-κ ]lanthanum(III)} dinitrate hemihydrate.
Acta Crystallogr E Crystallogr Commun
January 2025
Département de Chimie Faculté des Sciences et Techniques Université Cheik Anta Diop Dakar Senegal.
In the binuclear title complex, [La(CHO)(CHN)(HO)](NO)·0.5HO, the two lanthanum ions are nine coordinate in a distorted trigonal-prismatic geometry. Each La ion is bonded to three N atoms of the Schiff base, 1-(pyridin-2-yl)-2-(pyridin-2-yl-methyl-ene)hydrazine and is coordinated by one acetate group, which acts in -bidentate mode and two acetate groups that act in -mode between the two La ions.
View Article and Find Full Text PDFA new hydrated crystalline form of -[()-(4-hy-droxy-phen-yl)methyl-idene]-1-1,2,4-triazol-3-amine and its anti-fungal activity.
Acta Crystallogr E Crystallogr Commun
January 2025
Synchrotron SOLEIL, L'Orme des Merisiers, BP48, Saint Aubin, 91192, Gif-sur-Yvette, France.
The synthesis, crystal structure, Hirshfeld analysis, and anti-fungal assessment of a new monohydrated Schiff base with a triazole moiety are reported. The structural study revealed the presence of three significant hydrogen bonds (N-H⋯N, O-H⋯N, and O-H⋯O), which contribute to the cohesion of the crystal. These bonds generate two-dimensional layers parallel to the plane, built on the basis of rings with the graph-set motifs (8) and (24).
View Article and Find Full Text PDFSynthesis, crystal structure, Hirshfeld surface analysis and DFT calculations of the coordination compound tetra-aqua-bis-{2-[(5-methyl-1,3,4-thia-diazol-2-yl)sulfan-yl]acetato-κ}cobalt(II).
Acta Crystallogr E Crystallogr Commun
January 2025
A novel coordination compound, [Co()(HO)], was synthesized from aqueous solutions of Co(NO) and the ligand 2-[(5-methyl-1,3,4-thia-diazol-2-yl)sulfan-yl]acetic acid (H, CHNOS). In the monoclinic crystals (space group 2/), the cobalt(II) ion is located about a centre of symmetry and is octa-hedrally coordinated by two anions in a monodentate fashion through carboxyl O atoms and by four water mol-ecules. A relatively strong hydrogen bond between one of the water mol-ecules and the non-coordinating carboxyl-ate O atom consolidates the conformation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!