AI Article Synopsis
- - Autogenous dentin matrix (ADM), sourced from a patient's own extracted teeth, serves as a promising grafting material in reconstructive dentistry due to its low rejection rates and osteoinductive properties.
- - Research, including animal studies, has demonstrated ADM's effectiveness in various applications like preserving extraction sites and augmenting the maxillary sinus, making it a strong alternative to traditional bone grafts.
- - Despite its potential, the long-term effectiveness of ADM in bone regeneration is not well-studied, and there is a need for standardized preparation methods, which this paper aims to address by reviewing its composition and mechanisms.
Article Abstract
Autogenous dentin matrix (ADM), derived from a patient's extracted tooth, can be repurposed as an autologous grafting material in reconstructive dentistry. Extracted teeth provide a source for ADM, which distinguishes itself with its low rejection rate, osteoinductive capabilities and ease of preparation. Consequently, it presents a viable alternative to autogenous bone. Animal studies have substantiated its effective osteoinductive properties, while its clinical applications encompass post-extraction site preservation, maxillary sinus floor augmentation, and guided bone tissue regeneration. Nevertheless, the long-term efficacy of ADM applied in bone regeneration remains underexplored and there is a lack of standardization in the preparation processes. This paper comprehensively explores the composition, mechanisms underlying osteoinductivity, preparation methods, and clinical applications of ADM with the aim of establishing a fundamental reference for future studies on this subject.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346879 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000039422 | DOI Listing |
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