This study explores an eco-friendly method for synthesizing Cobalt oxide nanoparticles (CoONPs) using extracted carboxymethyl cellulose (CMC) as a reducing and stabilizing agent. The CoONPs, characterized via various analyses, demonstrated a crystalline structure with sizes ranging from 10.9 to 28.2 nm. Microscopic imaging confirmed a uniform spherical morphology with an average diameter of 27.2 nm. The biological activities of CoONPs were investigated extensively, highlighting their superior antibacterial efficacy compared to amoxicillin-clavulanic acid. These nanoparticles exhibited potent antioxidant properties and demonstrated safety for potential applications based on erythrocyte viability results. Additionally, CoONPs displayed significant potency against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and showed promising α-amylase enzyme inhibitory activity, highlighting their multifunctional therapeutic potential as antioxidant, antibacterial, anticancer, and alpha-amylase inhibition assay.
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| http://dx.doi.org/10.1016/j.ijbiomac.2024.135028 | DOI Listing |
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