AI Article Synopsis
- Influenza B virus can cause myocarditis, a serious heart condition, especially in rare cases like that of a 7-year-old boy who developed severe symptoms and ultimately died from multi-organ failure despite intensive care.
- Treatment included advanced medical interventions such as ECMO and CRRT, but the case emphasizes the rapid progression and challenges of managing fulminant myocarditis.
- The literature indicates that this condition mainly affects girls and there are few pediatric instances; however, anti-thymocyte globulin therapy shows promise as a potential treatment avenue.
Article Abstract
Background: Influenza B virus induced myocarditis is a rare complication with potentially wide variations in severity and clinical presentation, and the pathogenesis is unclear.
Case Presentation: We describe a rare case of a 7-year-old boy who developed fulminant myocarditis (FM) due to influenza B virus infection. Treatment measures included mechanical ventilation, vasoactive agents, Extracorporeal membrane oxygenation (ECMO), Continuous Renal Replacement Therapy (CRRT), anti-inflammatory, antiviral, anti-infection, and enteral nutrition support. After 10 days of treatment, the patient succumbed to multiorgan failure.
Conclusions: After a systematic review of the literature, we found that this disease predominantly affects females, with pediatric cases exceedingly rare. Fulminant myocarditis (FM) progresses rapidly, poses significant treatment challenges sporadic, and carries a poor prognosis. Interestingly, literature reports suggest that anti-thymocyte globulin therapy may have a positive impact in treating FM, potentially offering new insights into its pathogenesis and clinical management.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344422 | PMC |
| http://dx.doi.org/10.1186/s13019-024-02997-0 | DOI Listing |
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