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Noninvasive Quantitative CT for Diffuse Liver Diseases: Steatosis, Iron Overload, and Fibrosis.
Radiographics
January 2025
From the Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, E3/311 Clinical Science Center, Madison, WI 53792-3252; and the American College of Radiology (ACR) Institute for Radiologic Pathology, Silver Spring, Md.
Chronic diffuse liver disease continues to increase in prevalence and represents a global health concern. Noninvasive detection and quantification of hepatic steatosis, iron overload, and fibrosis are critical, especially given the many relative disadvantages and potential risks of invasive liver biopsy. Although MRI techniques have emerged as the preferred reference standard for quantification of liver fat, iron, and fibrosis, CT can play an important role in opportunistic detection of unsuspected disease and is performed at much higher volumes.
View Article and Find Full Text PDFInvited Commentary: Considerations for Opportunistic Screening for Diffuse Liver Disease at Routine Abdominal CT.
Radiographics
January 2025
From the Department of Radiology and Biomedical Imaging, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143-0628.
Hepatitis E virus infection after CAR T-cell treatment: An important complication in patients already facing significant health challenges.
Br J Haematol
December 2024
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Cancer patients with haematological malignancies are at risk for chronic hepatitis E virus infection following chimeric antigen receptor (CAR) T-cell therapy. Strong clinical suspicion is essential for the early diagnosis and prompt treatment of this difficult-to-treat type of viral hepatitis. Commentary on: Schwarz et al.
View Article and Find Full Text PDFLife After the HSIF: Lessons From Diffusion of Innovation for Sustaining the Impact of Embeddedness Comment on "Early Career Outcomes of Embedded Research Fellows: An Analysis of the Health System Impact Fellowship Program".
Int J Health Policy Manag
December 2024
Implementation Scient Team, Health Innovation Hub, Nova Scotia Health, Halifax, NS, Canada.
Article Synopsis
- Kasaai and colleagues investigate the career outcomes of alumni from the CIHR's Health System Impact Fellowship, finding that all participants from the 2017-2019 cohort are employed and predominantly work in Canada across various sectors.
- The study reveals that 37% of alumni engage in "hybrid" roles that combine academic work with other sectors, indicating a shift in career paths post-fellowship while also raising concerns about maintaining academic partnerships.
- Utilizing the Diffusion of Innovations framework, the commentary discusses risks like decentralization and limited training, proposing strategies to enhance network connections, focus on impactful innovations, and foster adaptability to support the long-term success of these embedded scholars.
Commentary: Bridging and Reducing the Gaps Between Research and Practice: Pathways to Outcomes and the Interactive Systems Framework for Dissemination and Implementation 2.0.
Eval Health Prof
December 2024
Wandersman Center, Columbia, SC, USA.
There are many ways proposed to achieve better societal outcomes (e.g., in health, education, and well-being) including: (1) bridging research and practice, (2) building the motivation and capacity of service delivery organizations (e.
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