Background: Longitudinal studies can generate valuable scientific knowledge, but can be compromised by systematic attrition. Previous research shows that sociodemographic characteristics (eg, ethnicity, age, educational level, socioeconomic circumstances) are associated with attrition rates. However, little is known about whether these characteristics differ by ethnicity, and how this impacts cohort retention strategies.
Methods: Using antenatal to 12-year data from the birth cohort study (N=6743), we examined transversal response rates by ethnicity (Māori, Pacific, Asian, European), used sequence analysis and cluster analysis to identify unique longitudinal response patterns, and binary logistic regression to examine ethnic-specific sociodemographic characteristics associated with these response patterns.
Results: The overall response rate at 12 years was 71.0%, with ethnic differences in response rates widening over the six data collection waves. Three longitudinal response patterns were identified: frequent responders (65.2%), intermittent non-responders (29.6%) and frequent non-responders (5.2%). Sociodemographic characteristics such as younger maternal age and lower maternal education were associated with a higher likelihood of membership in the non-response clusters across all ethnic groups. However, there were also important nuances by ethnicity. Individual level factors (eg, household material deprivation and maternal general health) tended to be associated with non-response for Europeans, whereas structural level factors (eg, area-level deprivation and racial discrimination) tended to be associated with non-response for Māori, Pacific and Asian peoples.
Conclusion: Ethnic differences in longitudinal response patterns are due to multiple factors of disadvantage, and therefore require targeted retention strategies. Stratifying analyses by ethnicity is important for revealing nuanced insights.
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http://dx.doi.org/10.1136/jech-2024-222428 | DOI Listing |
Int J Mol Sci
December 2024
College of Agricultural, Tarim University, Alar 843300, China.
wilt (VW) caused by (Vd) is a devastating fungal cotton disease characterized by high pathogenicity, widespread distribution, and frequent variation. It leads to significant losses in both the yield and quality of cotton. Identifying key non-synonymous single nucleotide polymorphism (SNP) markers and crucial genes associated with VW resistance in and , and subsequently breeding new disease-resistant varieties, are essential for VW management.
View Article and Find Full Text PDFMolecules
January 2025
Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus Materials, Yunnan International Joint Laboratory of Sustainable Polymers, The Higher Educational Key Laboratory for Phosphorus Chemical Engineering of Yunnan Province, Faculty of Chemical Engineering, Kunming University of Science and Technology, Kunming 650500, China.
The growing demand for sustainable energy storage solutions has underscored the importance of phase change materials (PCMs) for thermal energy management. However, traditional PCMs are always inherently constrained by issues such as leakage, poor thermal conductivity, and lack of solar energy conversion capacity. Herein, a multifunctional composite phase change material (CPCM) is developed using a balsa-derived morphology genetic scaffold, engineered via bionic catechol surface chemistry.
View Article and Find Full Text PDFBMC Nurs
January 2025
Spaarne Gasthuis Academy, Spaarne Gasthuis Hospital, Hoofddorp, the Netherlands.
Background: Addressing the growing challenge of nurse retention requires coordinated actions at national and global levels to improve recruitment, retention policies, and investments in the nursing work environment. The nursing work environment, defined as the "organizational characteristics of a work setting that facilitate or constrain professional nursing practice", is critical in influencing whether nurses decide to leave their jobs. This study investigates the impact of differentiated nursing practices - which involved tailoring roles and responsibilities based on nurses' training, skills, and experience in Dutch hospitals - and investigated their impact on the nursing work environment and turnover intention (i.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
We conducted a phase I trial to determine the optimal dose of triplet therapy with the tyrosine kinase inhibitor sitravatinib plus nivolumab plus ipilimumab in 22 previously untreated patients with advanced clear cell renal cell carcinoma. The primary endpoint was safety. Secondary endpoints were objective response rate (ORR), disease control rate (DCR), duration of response (DOR), progression-free survival (PFS), overall survival (OS), 1-year survival probability, and sitravatinib pharmacokinetics.
View Article and Find Full Text PDFRMD Open
December 2024
Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark.
Background: The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is a novel questionnaire of global functioning for patients with axial spondyloarthritis (SpA).
Objective: The objective was to assess the construct validity, discriminatory ability and responsiveness of ASAS HI in relation to patient-reported outcome measures (PROMs), MRI and radiography.
Methods: Data from two longitudinal studies with tumour necrosis factor inhibitor (TNFi) initiation (novel MRI And biomarkers in Golimumab-treated patients with axial spondyloarthritis (MANGO): n=45) respectively tapering (Dose adjustment of Biological treatment in patients with SpA (DOBIS): n=106) were used.
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