ECOTOXr: An R package for reproducible and transparent retrieval of data from EPA's ECOTOX database.

Chemosphere

Dept. Wageningen Marine Research, Wageningen University and Research Center, P.O. Box 57, Den Helder, 1780AB, the Netherlands. Electronic address:

Published: September 2024

The US EPA ECOTOX database provides key ecotoxicological data that are crucial in environmental risk assessment. It can be used for computational predictions of toxicity or indications of hazard in a wide range of situations. There is no standardised or formalised method for extracting and subsetting data from the database for these purposes. Consequently, results in such meta-analyses are difficult to reproduce. The present study introduces the software package ECOTOXr, which provides the means to formalise data retrieval from the ECOTOX database in the R scripting language. Three cases are presented to evaluate the performance of the package in relation to earlier data extractions and searches on the website. These cases demonstrate that the package can reproduce data sets relatively well. Furthermore, they illustrate how future studies can further improve traceability and reproducibility by applying the package and adhering to some simple guidelines. This contributes to the FAIR principles, credibility and acceptance of research that uses data from the ECOTOX database.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemosphere.2024.143078DOI Listing

Publication Analysis

Top Keywords

ecotox database
16
data
7
database
5
ecotoxr package
4
package reproducible
4
reproducible transparent
4
transparent retrieval
4
retrieval data
4
data epa's
4
ecotox
4

Similar Publications

This study aimed to develop a bioavailability-based effects assessment method for nickel (Ni) to derive acute freshwater environmental thresholds in Europe. The authors established a reliable acute freshwater Ni ecotoxicity database covering 63 different freshwater species, and the existing acute Ni bioavailability models for invertebrates were revised. A single average invertebrate bioavailability model was proposed, in which the protective effects of Ca2+ and Mg2+ on Ni2+ toxicity were integrated as a single-site competition effect at the Ni biotic ligand.

View Article and Find Full Text PDF

Assessment of potential impacts of chemicals on the environment traditionally involves regulatory standard data requirements for acute aquatic toxicity testing using algae, daphnids and fish (e.g., OECD test guidelines (TG) 201, 202, and 203, respectively), representing different trophic levels.

View Article and Find Full Text PDF

Microcontaminants (MCs) and microplastics (MPs) originating from the textile sector are today receiving a great deal of attention due to potential environmental concerns. Environmental pressures and impacts related to the textile system include not only the use of resources (, water) but also the release of a wide variety of pollutants. This review's main objective is to highlight the presence of textile MCs and MPs in water, in their full path from textile factories (from raw materials to the final product) to wastewater treatment plants (WWTPs), and finally to the receiving surface waters.

View Article and Find Full Text PDF

The global decline in bee populations poses significant risks to agriculture, biodiversity, and environmental stability. To bridge the gap in existing data, we introduce ApisTox, a comprehensive dataset focusing on the toxicity of pesticides to honey bees (Apis mellifera). This dataset combines and leverages data from existing sources such as ECOTOX and PPDB, providing an extensive, consistent, and curated collection that surpasses the previous datasets.

View Article and Find Full Text PDF

The RISMEAU project ( - Risks related to residues of pharmaceuticals and biocides, and antimicrobial resistance of human and veterinary origin on the water resources of the 2083 km Arve catchment located in the French Alps) was implanted from 2018 to 2024 on the SIPIBEL observatory. It was devoted to the evaluation of (i) transfers of and processes related to pharmaceutical residues and biocides from both urban sludge and manure spread on fields as fertilisers, and (ii) the environmental impacts of land spreading, in particular the ecotoxicological risks and antimicrobial resistance dissemination. The methodology was based on the physico-chemical, ecotoxicological and antimicrobial resistance (AMR - assessed by molecular biology) characterisation of leachate and soil matrices samples, and focused on organic waste products application at locally representative agronomic rates.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!