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Pediatric Soft Tissue Sarcoma in Limb-Girdle Muscular Dystrophy: Molecular Findings and Clinical Implications.
Am J Case Rep
December 2024
Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.
BACKGROUND Limb-girdle muscular dystrophy recessive 1 (LGMDR1) is an autosomal recessive degenerative muscle disorder characterized by progressive muscular weakness caused by pathogenic variants in the CAPN3 gene. Desmoplastic small round cell tumors (DSRCT) are ultra-rare and aggressive soft tissue sarcomas usually in the abdominal cavity, molecularly characterized by the presence of a EWSR1::WT1 fusion transcript. Mouse models of muscular dystrophy, including LGMDR1, present an increased risk of soft tissue sarcomas.
View Article and Find Full Text PDFMeasuring the impact of COVID-19 exposure on reporting of intimate partner violence in India using an intent-to-treat framework.
Sci Rep
December 2024
International Institute for Population Sciences, Mumbai, Maharashtra, 400088, India.
The COVID-19 pandemic has not only posed alarming health challenges but also exacerbated the scenarios of intimate partner violence (IPV) against women globally. While global studies indicate a conspicuous increase in IPV during COVID-19 lockdowns; Indian studies exhibit mixed evidence. This ambiguity in world's most populous country underscores a greater need to examine the nexus between exposure to COVID-19 and IPV using a large nationally representative sample of India.
View Article and Find Full Text PDFFactors influencing early postnatal care use among postpartum women in Afghanistan.
Sci Rep
December 2024
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Using postnatal care (PNC) within the first week following childbirth is crucial, as both the mother and her baby are particularly vulnerable to infections and mortality during this period. In this study, we examined the factors associated with early postnatal care (EPNC) use in Afghanistan. We used data from the multiple indicator cluster survey (MICS) 2022-2023.
View Article and Find Full Text PDFForgetting is comparable between healthy young and old people.
Sci Rep
December 2024
Institute of Psychology, University of Bern, Bern, Switzerland.
Aging is typically associated with declines in episodic memory, executive functions, and sleep quality. Therefore, the sleep-dependent stabilization of episodic memory is suspected to decline during aging. This might reflect in accelerated long-term forgetting, which refers to normal learning and retention over hours, yet an abnormal retention over nights and days.
View Article and Find Full Text PDFThe effect of Internet+ -based extracurricular running exercise on students' physical fitness.
Sci Rep
December 2024
Department of Physical Education, Guilin Medical University, Guilin, 541004, Guangxi, China.
The application of the Internet combined with extracurricular running exercise plays an important role in promoting the reform of school physical education teaching and the healthy development of students' physical fitness. 2379 students of Guilin Medical College used the Flash Campus APP for 30 weeks of running exercise during the school period, and the Wilcoxon test and t-test were used to statistically test the data of 50 m, standing long jump, lung capacity, seated forward bending, height, and body weight; men's pull-ups, 1,000 m; and women's sit-ups, 800 m pre- and post-tests. The Z/t values of men's 50 m, standing long jump, pull-ups, and lung capacity; women's 50 m running, standing long jump, sit-ups, lung capacity, and sitting prone flexion after extracurricular running exercise were - 3.
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