Background: Angular deformity in the lower extremity can result in pain, gait disturbance, cosmetic deformity and joint degeneration. Up until the introduction of guided growth, which has since become the widely accepted treatment for frontal plane angular angular deformity around the knee in skeletally immature patients, treatment consisted of staples, corrective osteotomy or an angular epiphysiodesis. Guided growth modulation uses the tension band principle with the goal of treatment being to normalise the lower limb mechanical axis resulting in lower morbidity than previous treatments. In order to assess the success of this procedure we reviewed our results in an attempt to identify patients who may not benefit from this elegant procedure.
Methods: We performed a retrospective review of prospectively collected surgical records and diagnostic imaging in our paediatric tertiary national referral centre to identify all patients who had guided growth surgery for coronal plane angular deformity of the knee from 2007 to 2023. We noted the patient demographics, diagnosis, peri-operative experience and outcome. All patients were followed until skeletal maturity, until their hardware was removed or at least 2 years.
Results: Two hundred thirty-six patients were assessed for eligibility. Of the 282 treated knees which met the criteria for final assessment 55 (19.5%) were unsuccessful. Complications were few but included infection and metal-work prominence. Procedures that were less likely to be successfully included growth disturbances following trauma (18.8% failure) or infection (40%), tumour (66.6%), mucopolysaccharidoses type I (15.7%), spondyloepiphyseal dysplasia (25%) or Blount's disease (60%). Idiopathic angular deformity showed an 89.5% success rate with guided growth.
Conclusion: In our hands, guided growth had an 80.5% success rate when all diagnoses were considered. We continue to advocate the use of guided growth as a successful treatment option for skeletally immature patients with limb deformity however caution should be employed when considering its use in certain patient groups.
Level Of Evidence: Level III, retrospective cohort study.
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http://dx.doi.org/10.1007/s11845-024-03794-3 | DOI Listing |
Planta
January 2025
Department of Fruit Science, College of Horticulture, Dr Yashwant Singh Parmar University of Horticulture and Forestry, Solan, Himachal Pradesh, 173230, India.
This review serves as a critical framework for guiding future research into the causes of russeting and the development of effective control strategies to enhance fruit quality. Russeting is a condition characterized by the formation of brown, corky patches on fruit skin which significantly impairs both the quality and market value of apples. This phenomenon arises from a complex interplay of various biotic and abiotic factors.
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June 2025
Environmental Science and Engineering Program, The University of Texas at El Paso, El Paso, TX 79968, USA.
We describe an agent-based model purposed for social learning, which was developed by stakeholders, with the technical assistance of professional modelers, to facilitate stakeholder involvement in modeling issues related to the development of an adaptive environmental management plan for the Texas Gulf Coast (USA) estuaries. Stakeholders developed the model during six workshops that spanned a three-year period, and used the model to simulate the population dynamics (recruitment, growth, movement, and mortality) of blue crabs () in the Aransas and Copano Bays in response to various freshwater inflow and harvest scenarios. Results of scenarios representing normal, low, and high harvest levels indicated little effect on blue crab abundances, but harvests increased ≈75 % when harvest level was doubled and decreased ≈50 % harvest level was halved.
View Article and Find Full Text PDFVet Res
January 2025
Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Porcine reproductive and respiratory syndrome virus (PRRSV) presents significant economic challenges to the global pork industry due to its ability to mutate rapidly. The current commercial vaccines have limited effectiveness, and there are strict restrictions on the use of antiviral chemical drugs. Therefore, it is urgent to identify new strategies for preventing and controlling PRRSV infections.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Medical Education, Ajou University School of Medicine, Suwon, Korea (the Republic of)
Objectives: The study aims to explore the workplace learning experiences of medical faculty in critical care specialties at a university hospital, focusing on how they develop their professional identity and construct the meaning of their work.
Design: Qualitative, phenomenological study.
Setting: The current study was conducted at a university hospital in South Korea between November 2022 and October 2023.
Curr Opin Pediatr
January 2025
Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Purpose Of Review: The use of body composition to assess the quality of infant growth may add valuable information to pediatric clinical care. Preterm infants have differences in their fat and muscle mass development compared with infants born at term, which may be related to their early nutritional exposures. This review focuses on recent studies examining early nutrition in preterm infants and related body composition outcomes in the newborn period and beyond.
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