AI Article Synopsis
- Vitamin C deficiency, or scurvy, is an ancient disease that still affects specific groups today, including smokers, alcoholics, the elderly, and those with absorption issues.
- Symptoms include perifollicular hemorrhage, corkscrew hairs, and petechiae that can worsen to more severe bruising.
- Early diagnosis helps to avoid unnecessary tests, and with vitamin C treatment, patients like a 45-year-old alcoholic can see quick improvements in their condition.
Article Abstract
Vitamin C deficiency, otherwise known as scurvy, is one the oldest known diseases. Although its prevalence has substantially diminished, certain populations such as smokers, alcoholics, elderly, and those with malabsorptive syndromes remain at risk. Deficiency presents with perifollicular hemorrhage, corkscrew hairs, and petechiae that can evolve into ecchymoses and purpura. Diagnosis starts with clinical suspicion and is confirmed with plasma and leukocyte ascorbic acid levels. Early suspicion is key. Treatment with vitamin C offers an excellent prognosis and avoids unnecessary workup for differential diagnoses. In our case, a 45-year-old male alcoholic with progressively worsening symptoms was found to have scurvy. Treatment was initiated with vitamin C supplementation, and he had remarkable improvement in his symptoms within weeks. This case demonstrates that scurvy is not a disease of history and must be considered in modern medicine, especially as homelessness with concomitant poor nutrition continues to increase.
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| http://dx.doi.org/10.1038/s41430-024-01498-6 | DOI Listing |
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