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| http://dx.doi.org/10.1016/j.jaad.2024.07.1479 | DOI Listing |
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Biomarkers.
Alzheimers Dement
December 2024
Janssen Research & Development, LLC, a Johnson & Johnson company, Boston, MA, USA.
Background: Precision neuroscience is emerging as a transformative approach that aims to identify the right treatment for the right patient at the right time. To enable this, it is important to move beyond the categorization of patients based on clinical symptoms towards a biological definition of disease. For Alzheimer's disease, significant progress has been made in this direction, with the development of the "A/T/N" biomarker framework that classifies patients based on underlying pathophysiology.
View Article and Find Full Text PDFDementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Center for Life Ethics, University of Bonn, Bonn, Germany.
Background: Driven by (bio-)medical and technical developments, advanced non-invasive methods for estimating the risk of Alzheimer's dementia (ADD) are increasingly emerging. In the future, such methods could eventually become available for individuals in asymptomatic and preclinical stages of Alzheimer's disease (e.g.
View Article and Find Full Text PDFPurpose: For youth walking with a parent's younger-onset dementia diagnosis, our voices are the softest, yet our journey is often the hardest. We are helping to open the shades and bring light. We are telling the stories of our Mother's and our Father's.
View Article and Find Full Text PDFChallenges of E-Waste Dismantling in China.
Toxics
November 2024
School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Hangzhou 310053, China.
Electronic and electrical products have deeply permeated all aspects of life, bringing a lot of convenience to individuals. However, the generation of e-waste after their end-of-life has resulted in serious risks both to the ecological environment and human health due to a lack of scientific and effective recycling and treatments. As two major types of components in e-waste, heavy metals and plastics can not only directly enter the human body via inhalation, ingestion, and skin absorption, but also accumulate in the human body indirectly through the food chain.
View Article and Find Full Text PDFComparative Transcriptome Analysis Reveals Mechanisms of Differential Salinity Tolerance Between and .
Genes (Basel)
December 2024
Key Laboratory of Sweet Potato Biology and Biotechnology, Ministry of Agriculture and Rural Affairs/Beijing Key Laboratory of Crop Genetic Improvement/Laboratory of Crop Heterosis & Utilization and Joint Laboratory for International Cooperation in Crop Molecular Breeding, Ministry of Education, College of Agronomy & Biotechnology, China Agricultural University, Beijing 100193, China.
Background: and have obvious morphological features and strongly tolerate saline-alkali environments. However, the mechanisms that lead to the differences in saline-alkali tolerance between them remain unclear.
Methods: In this study, we employed comparative transcriptome analysis to investigate and under saline-alkali stress.
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