Modern generative artificial intelligence techniques like retrieval-augmented generation (RAG) may be applied in support of precision oncology treatment discussions. Experts routinely review published literature for evidence and recommendations of treatments in a labor-intensive process. A RAG pipeline may help reduce this effort by providing chunks of text from these publications to an off-the-shelf large language model (LLM), allowing it to answer related questions without any fine-tuning. This potential application is demonstrated by retrieving treatment relationships from a trusted data source (OncoKB) and reproducing over 80% of them by asking simple questions to an untrained Llama 2 model with access to relevant abstracts.
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http://dx.doi.org/10.3233/SHTI240575 | DOI Listing |
J Craniomaxillofac Surg
January 2025
Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
The potential of large language models (LLMs) in medical applications is significant, and Retrieval-augmented generation (RAG) can address the weaknesses of these models in terms of data transparency and scientific accuracy by incorporating current scientific knowledge into responses. In this study, RAG and GPT-4 by OpenAI were applied to develop GuideGPT, a context aware chatbot integrated with a knowledge database from 449 scientific publications designed to provide answers on the prevention, diagnosis, and treatment of medication-related osteonecrosis of the jaw (MRONJ). A comparison was made with a generic LLM ("PureGPT") across 30 MRONJ-related questions.
View Article and Find Full Text PDFJ Am Med Inform Assoc
January 2025
Division of Computational Health Sciences, Department of Surgery, University of Minnesota, Minneapolis, MN 55455, United States.
Objective: To develop an advanced multi-task large language model (LLM) framework for extracting diverse types of information about dietary supplements (DSs) from clinical records.
Methods: We focused on 4 core DS information extraction tasks: named entity recognition (2 949 clinical sentences), relation extraction (4 892 sentences), triple extraction (2 949 sentences), and usage classification (2 460 sentences). To address these tasks, we introduced the retrieval-augmented multi-task information extraction (RAMIE) framework, which incorporates: (1) instruction fine-tuning with task-specific prompts; (2) multi-task training of LLMs to enhance storage efficiency and reduce training costs; and (3) retrieval-augmented generation, which retrieves similar examples from the training set to improve task performance.
Turk Psikiyatri Derg
January 2025
Mental disorders are a critical global public health problem due to their increasing prevalence, rising costs, and significant economic burden. Despite efforts to increase the mental health workforce in Türkiye, there is a significant shortage of psychiatrists, limiting the quality and accessibility of mental health services. This review examines the potential of artificial intelligence (AI), especially large language models, to transform psychiatric care in the world and in Türkiye.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Key Laboratory of Urban Environment and Health, Ningbo Observation and Research Station, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, Peoples R China.
Increasing antimicrobial resistance (AMR) poses a substantial threat to global health and economies, which has led many countries and regions to develop AMR National Action Plans (NAPs). However, inadequate logistical capacity, funding, and essential information can hinder NAP policymaking, especially in low-to-middle-income countries (LMICs). Therefore, major gaps exist between aspirations and actions, such as fully operationalized environmental AMR surveillance programs in NAPs.
View Article and Find Full Text PDFSensors (Basel)
December 2024
School of Biological and Environmental Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, UK.
Camera traps offer enormous new opportunities in ecological studies, but current automated image analysis methods often lack the contextual richness needed to support impactful conservation outcomes. Integrating vision-language models into these workflows could address this gap by providing enhanced contextual understanding and enabling advanced queries across temporal and spatial dimensions. Here, we present an integrated approach that combines deep learning-based vision and language models to improve ecological reporting using data from camera traps.
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