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Gastrointestinal Alpha Heavy Chain Disease With Persistent Colonization and Refractory Giardiasis. | LitMetric

Alpha heavy chain disease (αHCD) is a rare variant of the mucosa-associated lymphoid tissue lymphoma characterized by expression of a monotypic truncated immunoglobulin α heavy chain. αHCD frequently involves the gastrointestinal (GI) tract, and its pathogenesis has been linked to clonal B-cell expansion from chronic immune stimulation by infectious agents. We report a rare case of GI αHCD with 5 concomitant pathogens identified on a GI multiplex real-time polymerase chain reaction panel, featured by persistent colonization and refractory giardiasis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11340919PMC
http://dx.doi.org/10.14309/crj.0000000000001467DOI Listing

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