AI Article Synopsis
- Mitochondria play a crucial role in cell function and are linked to various diseases, leading to the development of targeted imaging and treatment strategies.
- Theranostics combines diagnosis and therapy in a single agent, simplifying treatment and improving drug evaluation by focusing on mitochondria-specific interventions.
- Recent advancements in mitochondria-targeting theranostic materials have been summarized, highlighting their design and effectiveness in localized disease treatment and diagnosis.
Article Abstract
For its vital role in maintaining cellular activity and survival, mitochondrion is highly involved in various diseases, and several strategies to target mitochondria have been developed for specific imaging and treatment. Among these approaches, theranostic may realize both diagnosis and therapy with one integrated material, benefiting the simplification of treatment process and candidate drug evaluation. A variety of mitochondria-targeting theranostic agents have been designed based on the differential structure and composition of mitochondria, which enable more precise localization within cellular mitochondria at disease sites, facilitating the unveiling of pathological information while concurrently performing therapeutic interventions. Here, progress of mitochondria-targeting theranostic materials reported in recent years along with background information on mitochondria-targeting and therapy have been briefly summarized, determining to deliver updated status and design ideas in this field to readers.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335472 | PMC |
| http://dx.doi.org/10.1002/EXP.20230063 | DOI Listing |
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