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| http://dx.doi.org/10.1093/gastro/goae080 | DOI Listing |
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Latest revisions to the International Health Regulations will fail to prevent future travel chaos.
BMJ Glob Health
January 2025
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
The poor management of public health risks associated with travel by most countries proved among the most contentious issue areas during the COVID-19 pandemic. Evidence from previous outbreaks suggested travel restrictions were largely unnecessary and counterproductive to timely reporting. This led to initial WHO recommendations against the use of travel restrictions.
View Article and Find Full Text PDFOn the formation and stability mechanisms of diverse lipid-based nanostructures for drug delivery.
Adv Colloid Interface Sci
January 2025
Department of Chemistry and Biotechnology, School of Science, Computing and Engineering Technologies, Swinburne University of Technology, Melbourne, Australia.
In the evolving landscape of nanotechnology and pharmaceuticals, lipid nanostructures have emerged as pivotal areas of research due to their unique ability to mimic biological membranes and encapsulate active molecules. These nanostructures offer promising avenues for drug delivery, vaccine development, and diagnostic applications. This comprehensive review explores the complex mechanisms underlying the formation and stability of various lipid nanostructures, including lipid liquid crystalline nanoparticles and solid lipid nanoparticles.
View Article and Find Full Text PDFAssessing the disconnect between student interest and education in artificial intelligence in medicine in Saudi Arabia.
BMC Med Educ
January 2025
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Background: Although artificial intelligence (AI) has gained increasing attention for its potential future impact on clinical practice, medical education has struggled to stay ahead of the developing technology. The question of whether medical education is fully preparing trainees to adapt to potential changes from AI technology in clinical practice remains unanswered, and the influence of AI on medical students' career preferences remains unclear. Understanding the gap between students' interest in and knowledge of AI may help inform the medical curriculum structure.
View Article and Find Full Text PDFShaping epithelial tissues by stem cell mechanics in development and cancer.
Nat Rev Mol Cell Biol
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Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA.
Adult stem cells balance self-renewal and differentiation to build, maintain and repair tissues. The role of signalling pathways and transcriptional networks in controlling stem cell function has been extensively studied, but there is increasing appreciation that mechanical forces also have a crucial regulatory role. Mechanical forces, signalling pathways and transcriptional networks must be coordinated across diverse length and timescales to maintain tissue homeostasis and function.
View Article and Find Full Text PDFTerrestrial friction-reducing properties of mucus and scale anisotropy in the amphibious Northern Snakehead (Channa argus).
Integr Comp Biol
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Department of Biology, Henson School of Science and Technology, Salisbury University, Salisbury, MD 21801, USA.
The mucus coating around a fish's body is essential to its survival. It contains antimicrobial properties, aids in drag reduction, and protects against physical damage. It is versatile in the aquatic environment but little is known about the role of mucus in amphibious fishes.
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