Early comprehensive pulmonary rehabilitation for hospitalized patients with acute ex-acerbation of chronic obstructive pulmonary disease: a randomized controlled trial.

J Rehabil Med

Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China; Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China; Clinical Medical Research Center for Pulmonary and Critical Care Medicine in Hunan Province, Changsha, Hunan, China; Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, China.

Published: August 2024

AI Article Synopsis

  • The study aimed to determine the safety and effectiveness of early comprehensive pulmonary rehabilitation for patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD).
  • Involving 108 patients, the research measured outcomes like walking distance, quality of life, breathlessness, and muscle strength, finding significant improvements in walking distance and inspiratory muscle strength for those receiving rehabilitation compared to usual care.
  • The results suggest that early pulmonary rehabilitation is both safe and beneficial, offering noticeable improvements in patient outcomes and being recommended to start during the early stages of hospitalization.

Article Abstract

Objective: To investigate whether an early comprehensive pulmonary rehabilitation intervention initiated during hospital admission is safe and effective for patients with acute exacerbation of chronic obstructive pulmonary disease.

Design: Prospective randomized controlled study.

Subjects/patients: Patients with acute exacerbation of chronic obstructive pulmonary disease.

Methods: In total, 108 patients were randomized to the early comprehensive pulmonary rehabilitation and usual care groups within 48 hours. The 6-min walking distance, quality of life, breathlessness, and inspiratory muscle strength were measured on admission and discharge. Any adverse events of pulmonary rehabilitation were recorded.

Results: On discharge, the patients in the early comprehensive pulmonary rehabilitation group had a more significant improvement in the 6-min walking distance (47.5 vs 23.0, p = 0.04). There was no significant difference in quality of life and breathlessness between the 2 groups. In the early comprehensive pulmonary rehabilitation group, inspiratory muscle strength and peak inspiratory flow were significantly improved, and the changes were much more pronounced than in the usual care group. There were no adverse events.

Conclusion: Early comprehensive pulmonary rehabilitation is safe and effective for hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease, and should be performed during the early stage of hospitalization.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358843PMC
http://dx.doi.org/10.2340/jrm.v56.39953DOI Listing

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