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Coronary CT angiography-guided management of patients with stable chest pain: 10-year outcomes from the SCOT-HEART randomised controlled trial in Scotland.
Lancet
January 2025
British Heart Foundation Centre of Research Excellence, University of Edinburgh, Edinburgh, UK; Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.
Background: The Scottish Computed Tomography of the Heart (SCOT-HEART) trial demonstrated that management guided by coronary CT angiography (CCTA) improved the diagnosis, management, and outcome of patients with stable chest pain. We aimed to assess whether CCTA-guided care results in sustained long-term improvements in management and outcomes.
Methods: SCOT-HEART was an open-label, multicentre, parallel group trial for which patients were recruited from 12 outpatient cardiology chest pain clinics across Scotland.
Understanding social behaviours across neurodiverse young people: roles of social cognition and self-regulation.
BJPsych Open
January 2025
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Canada; Department of Psychology, Faculty of Arts & Science, University of Toronto, Canada; Department of Psychiatry, The Hospital for Sick Children, Toronto, Canada; Autism Research Centre, Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, National Taiwan University Hospital, Taiwan; and Department of Psychiatry, National Taiwan University College of Medicine, Taiwan.
Background: Differences in social behaviours are common in young people with neurodevelopmental conditions (NDCs). Recent research challenges the long-standing hypothesis that difficulties in social cognition explain social behaviour differences.
Aims: We examined how difficulties regulating one's behaviour, emotions and thoughts to adapt to environmental demands (i.
From patient to pioneer: The inspiring journey of Dr. Brian Moran.
Brachytherapy
January 2025
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
Use of Essential Medicines for Pain Relief and Palliative Care: A Global Consensus Process.
J Pain Symptom Manage
January 2025
International Association for Hospice and Palliative Care (T.P., L.D.L., L.R.), Houston, USA; University of Bonn (L.R.), Bonn, Germany.
Context: The WHO Model List of Essential Medicines includes 24 medications under the section Medicines for Pain and Palliative Care (EML). The Lancet Commission on Pain and Palliative Care developed the Lancet Essential Package (LEP), including 35 medications designed to alleviate serious health-related suffering worldwide.
Objectives: This study aims to provide recommendations on the appropriate use of essential of medicines in palliative care.
Is prolonged operative time associated with postoperative complications in liver surgery? An international multicentre cohort study of 5424 patients.
Surg Endosc
December 2024
Department of Surgery, Fondazione Poliambulanza Istituto Ospedaliero, Via Leonida Bissolati, 57, 25124, Brescia, Italy.
Article Synopsis
- The study investigates how the length of time taken during liver surgeries affects the likelihood of postoperative complications in patients undergoing different types of liver resections.
- A total of 5,424 patients were analyzed from multiple centers between 2000 and 2022, focusing on procedures like right hemihepatectomy, technically major resection, and left lateral sectionectomy.
- Results show that patients in the longest operative time group had a significantly higher risk of complications, particularly in various surgical approaches like open, laparoscopic, and robotic surgeries.
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