AI Article Synopsis
- The study of human working memory (WM) is crucial in neuroscience, but investigating the medial temporal lobe (MTL) has been challenging due to noninvasive method limitations.
- Recent advancements in intracranial neural recordings reveal that various MTL regions play unique roles in different aspects of WM and interact with each other and the wider brain network.
- These findings suggest that the MTL should be included in models of WM to better capture the complex neural mechanisms of WM, which could improve our understanding of its flexibility, adaptability, and precision.
Article Abstract
The study of human working memory (WM) holds significant importance in neuroscience; yet, exploring the role of the medial temporal lobe (MTL) in WM has been limited by the technological constraints of noninvasive methods. Recent advancements in human intracranial neural recordings have indicated the involvement of the MTL in WM processes. These recordings show that different regions of the MTL are involved in distinct aspects of WM processing and also dynamically interact with each other and the broader brain network. These findings support incorporating the MTL into models of the neural basis of WM. This integration can better reflect the complex neural mechanisms underlying WM and enhance our understanding of WM's flexibility, adaptability, and precision.
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| http://dx.doi.org/10.1016/j.tics.2024.07.008 | DOI Listing |
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