Custom sports mouthguards are used in various sports to protect teeth, temporomandibular joints, and soft tissues from impact forces. The present article demonstrates a digital workflow to fabricate a 3-dimensionally (3D) printed individualized sports mouthguard. An optical jaw tracking system is used to record a repeatable reference position, and mandibular excursive movements to achieve a completely balanced occlusion. The technique simplifies the fabrication of a custom-fit mouthguard over the conventional approach by providing increased thickness accuracy, control of design, and integration of jaw motion.
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http://dx.doi.org/10.1016/j.prosdent.2024.07.021 | DOI Listing |
Pathologie (Heidelb)
January 2025
MVZ Dermatopathologie Duisburg Essen GmbH, Essen, Deutschland.
As in general pathology, digitalization is also inexorably making its way into dermatopathology. This article examines the current state of digitalization in German dermatopathology laboratories based on the authors' own experiences, the current study situation, and a survey of members of the Dermatological Histology Working Group (ADH). Experiences with the establishment of a digital laboratory workflow, artificial intelligence (AI)-based assistance systems, and whole slide images (WSI)-based training programs are discussed.
View Article and Find Full Text PDFEpilepsia
January 2025
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Objective: Somatic variants causing epilepsy are challenging to detect, as they are only present in a subset of brain cells (e.g., mosaic), resulting in low variant allele frequencies.
View Article and Find Full Text PDFPathologica
December 2024
Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
The search for reliable prognostic markers in oral squamous cell carcinoma (OSCC) remains a critical need. Tumor-infiltrating lymphocytes (TILs), particularly T lymphocytes, play a pivotal role in the immune response against tumors and are strongly correlated with favorable prognoses. Computational pathology has proven highly effective for histopathological image analysis, automating tasks such as cell detection, classification, and segmentation.
View Article and Find Full Text PDFSmall Methods
January 2025
College of Control Science and Engineering, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou, Zhejiang Province, 310027, China.
J Dent Child (Chic)
September 2024
School of Dentistry, Ceuma University, Imperatriz, Maranhão, Brazil.
The quest for an esthetically pleasing smile is a key driver in seeking dental interventions aimed at achieving a more balanced and harmonious appearance. The purpose of this report is to discuss the restoration of conical lateral incisors in an 11-year-old patient. The treatment approach employed direct composite resin restorations associated with the Digital Smile Design (DSD) technology.
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