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DNA methylation analysis on anal swabs for anal cancer screening in people living with HIV.
J Infect Dis
December 2024
Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of Pathology, Boelelaan 1117, Amsterdam, The Netherlands.
Introduction: High-resolution anoscopy (HRA) to prevent anal cancer is complex and screening capacity is limited. Previously, we showed that DNA methylation analysis of anal high-grade squamous intraepithelial lesions (HSIL) biopsies can distinguish between HSIL with an increased cancer risk, and HSIL with a low cancer risk, in which treatment may be safely withheld. Here, we assessed the performance of methylation analysis in anal swabs to identify patients with underlying HSIL with an increased cancer risk.
View Article and Find Full Text PDFTransvaginal natural orifice specimen extraction surgery for left-sided colorectal resection: A single-centre cohort study.
J Minim Access Surg
December 2024
Department of Surgery, Division of Colorectal Surgery, China Medical University Hsinchu Hospital, Zhubei City, Taiwan.
Introduction: Transvaginal natural orifice specimen extraction surgery (NOSES) is an innovative and feasible approach for left-sided colorectal resections in females. This study aimed to report our experience with transvaginal NOSES for left-sided laparoscopic colorectal resections.
Patients And Methods: We analysed data for all patients with transvaginal extraction performed for left-sided laparoscopic colorectal resections between 2011 and 2021 at a tertiary teaching hospital in Taiwan.
Understanding human papillomavirus vaccine response and efficacy in people living with HIV: A systematic mixed studies review and meta-analysis.
PLOS Glob Public Health
December 2024
Department of International Health, Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Coinfection with human papillomavirus (HPV) and HIV compounds the risks of developing cervical, anal, and HPV-associated oral neoplasia. Safe prophylactic vaccines are available to prevent HPV infections in people with HIV(PWH). Yet, vaccine efficacy and duration of protection remain questionable.
View Article and Find Full Text PDFAutoFOX: An automated cross-modal 3D fusion framework of coronary X-ray angiography and OCT.
Med Image Anal
December 2024
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China; Department of Cardiovascular Medicine, University of Oxford, OX39DU, UK. Electronic address:
Article Synopsis
- Coronary artery disease (CAD) is a major global health issue, and combining coronary X-ray angiography (XA) with optical coherence tomography (OCT) can enhance diagnosis and treatment by providing detailed images of coronary anatomy and plaque structure.
- The new framework, AutoFOX, employs a deep learning model called TransCAN to accurately align 3D vascular images, achieving impressive alignment precision, especially at critical anatomical points.
- AutoFOX also includes innovative methods for reconstructing side branches and utilizes a diverse dataset for validation, demonstrating strong accuracy and reliability in assessing bifurcation lesions, which is essential for improving CAD management and procedures.
Dual-modality visual feature flow for medical report generation.
Med Image Anal
December 2024
Chongqing Key Laboratory of Image Cognition, College of Computer Science and Technology, Chongqing University of Posts and Telecommunication, Chongqing, 400065, China.
Medical report generation, a cross-modal task of generating medical text information, aiming to provide professional descriptions of medical images in clinical language. Despite some methods have made progress, there are still some limitations, including insufficient focus on lesion areas, omission of internal edge features, and difficulty in aligning cross-modal data. To address these issues, we propose Dual-Modality Visual Feature Flow (DMVF) for medical report generation.
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