Objective: The aim of the study is to evaluate the syndrome of PSAF-autoadaptation in patients with tumors of maxillofacial localization based on the analysis of the results of a survey of the patient's Voluntary Confidential Information Sheet (DDIV Sheet).
Material And Methods: The object of the study was 110 patients (39 men and 71 women (average age 58 years) with malignant neoplasms of the skin, tongue, bottom of the oral cavity, parotid salivary gland, upper jaw, submandibular salivary gland (stage II-IV of the disease). Rapid diagnostics of psycho-sensory-anatomical-functional-autoadaptation (PSAF) was performed by analyzing self-filled patient lists of DDIV with its self-assessment of the main complaints. After distributing complaints and manifestations of the disease into 4 clusters, the severity and structure of autoadaptation were calculated in points.
Results: It was found that in the majority of cancer patients in the preoperative period, complaints related to mental and functional clusters prevailed. At the same time, 80% of patients rated the degree of concern for their health as extremely alarming, and 20% as very anxious. In the postoperative period, the number of psychological complaints decreased and the number of complaints corresponding to anatomical, sensory and functional clusters increased.
Conclusion: The study of personal response to the disease according to PSAF-autoadaptation of cancer patients showed that the presence of a tumor lesion not only affects the internal picture of the disease, adversely affects the physical, mental and social well-being of patients, but also requires the involvement of psychologists, psychotherapists, clinical pharmacologists in the treatment of cognitive behavioral psychotherapy.
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http://dx.doi.org/10.17116/stomat202410304120 | DOI Listing |
Ann Diagn Pathol
January 2025
Department of Pathology, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke, Tochigi, Japan.
The tumor microenvironment is highly heterogeneous and consists of neoplastic cells and diverse stromal components, including fibroblasts, endothelial cells, pericytes, immune cells, local and bone marrow-derived stromal stem and progenitor cells, and the surrounding extracellular matrix. Although the significance of p16 and p53 has been reported in various tumor types, their involvement in the stromal cells of oral squamous cell carcinoma (OSCC) remains unclear. We performed immunohistochemical analyses of p16 and p53 expression in OSCC samples, Of the 116 samples, 74 showed p16-positive stromal cells, and 33 showed p53-positive stromal cells.
View Article and Find Full Text PDFCrit Rev Anal Chem
January 2025
Department of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Taif University, Taif, Saudi Arabia.
Organic fluorescence and colorimetric probes have emerged as vital tools for detecting metal ions, due to their high sensitivity, selectivity, and rapid response times. Copper, an essential trace element, plays a critical role in biological systems, yet its imbalance can lead to severe disorders such as neurodegenerative diseases, cancer, and Wilson's disease. Over the past few years, advancements in probe design have unlocked innovative avenues for not only detecting Cu in environmental and biological samples but also for visualizing its distribution through fluorescence imaging.
View Article and Find Full Text PDFCureus
December 2024
Oral and Maxillofacial Radiology, Henry M. Goldman School of Dental Medicine, Boston, USA.
A dentigerous cyst (DC) is the most common developmental cystic lesion of the jaws. Histologically, these cysts derive from the odontogenic epithelium that includes the reduced enamel epithelium, epithelial cell rests of Serres, and epithelial cell rests of Malassez. Radiographically, DCs are usually presented as well-defined radiolucencies associated with the crown of an unerupted tooth at the level of the cementoenamel junction (CEJ).
View Article and Find Full Text PDFCureus
December 2024
Oral and Maxillofacial Surgery, ITS Dental College, Hospital and Research Centre, Greater Noida, IND.
Introduction The role of concomitant chemoradiation therapy (CTRT) or radiation therapy (RT) is not well defined in operated cases of oral squamous cell carcinoma (OSCC) with positive perineural spread. The purpose of the study was to determine whether the use of concurrent CTRT or RT would enhance the five-year disease-free survival of patients with positive perineural invasion (PNI). Materials and methods Data were analysed retrospectively from January 2014 to December 2023.
View Article and Find Full Text PDFCase Rep Dent
January 2025
Department of Conservative Dentistry and Endodontics, College of Dental Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Pleomorphic adenoma (PA), the most common salivary gland tumor, presents unique challenges due to its diverse clinicopathologic features. The objective of this case series is to highlight the implication of detailed histopathological examination to guide appropriate diagnosis. This study reviews 10 cases of PA diagnosed at B.
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