The main objective of healthcare centers is to ensure a consistent and high-purity oxygen supply for the safety of patients. Pressure Swing Adsorption (PSA) is a commonly used technique for supplying medical oxygen by eliminating nitrogen from the ambient air. Due to the increased fire risk associated with oxygen, any malfunctions in the oxygen supply system can lead to serious hospital fires. This study aimed to assess the reliability of the oxygen supply system using Fault Tree Analysis (FTA) based on both the traditional method and Intuitionistic Fuzzy Analysis. FTA is a logical analysis method used to identify events that could result in an undesirable top event and calculate the probability of its occurrence. The FTA of the PSA system outlined the logical sequence of events that could lead to the release of oxygen as a top event. The study revealed that the failure of the pressure switch in the concentrator, inadequate sealing, and the use of inappropriate materials for the seals were the primary basic events that led to the release of oxygen. Additionally, this study utilized the Intuitionistic Fuzzy System to quantify experts' opinions, providing more flexibility in handling ambiguous situations and considering both membership and non-membership functions simultaneously.
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http://dx.doi.org/10.1016/j.heliyon.2024.e34649 | DOI Listing |
Cureus
December 2024
Department of Anesthesiology, University of Tsukuba, Tsukuba, JPN.
Introduction It has been known that progesterone has central effects, as measured by minimum alveolar concentration in various experimental settings. Previously, we showed that progesterone reduces the sevoflurane requirement for the loss of righting reflex (LORR) using male mice. However, the combination of progesterone and isoflurane has not been studied.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Gaziantep University, Gaziantep, Turkey.
Background: This study evaluates the effects of ozone on hard and soft tissue healing when a free tissue flap is used to close wound areas lacking primary closure over autogenous grafted sites.
Methods: In our study, 24 male Wistar rats were divided into four groups: two control groups and two ozone-treated groups. All rats underwent the same surgical procedure.
BMC Genomics
January 2025
College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, 266109, China.
Background: The cryoinjury of semen during cryopreservation reduces sperm motility, constraining the application of artificial insemination (AI) in bovine reproduction. Some fertility markers, related to sperm motility before and after freezing have been identified. However, little is known about the biological mechanism through which freezing reduces sperm motility.
View Article and Find Full Text PDFBiomed Pharmacother
January 2025
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), Argentina; Universidad Nacional de Cuyo, Facultad de Ciencias Médicas, Instituto de Bioquímica y Biotecnología, Avda. Libertador 80, Mendoza CP5500, Argentina. Electronic address:
A hypertonic solution of Ibuprofen (Ibu) was designed to nebulize, associating a low concentration of Ibu with L-Arginine (AR), to increase solubility and serve as a nitric oxide donor. To provide preclinical research human bronchial epithelial cells derived from a cystic fibrosis patient homozygous for the ΔF508 CFTR mutation (CFBE41o-) and mouse RAW 264.7 macrophages were pre-treated with Ibu (10-100 μM), AR (20 and 200 μM), or the combination Ibu-AR (10-100 μM).
View Article and Find Full Text PDFChem Rec
January 2025
Department of Chemical Engineering, King Fahd University of Petroleum and Minerals, Dhahran, 31261, Saudi Arabia.
In recent times, chemical looping offered a sustainable alternative for upgrading light hydrocarbons into olefins. Olefins are valuable platform chemicals that are utilized for diverse applications. To close the wide shortfall in their global supply, intensified efforts are ongoing to develop on-purpose production technologies.
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