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Laparoscopic Cholecystectomy in Cardiogenic Shock And Heart Failure. | LitMetric

AI Article Synopsis

  • Patients with cardiogenic shock or heart failure can develop ischemic cholecystitis, and while percutaneous cholecystostomy is commonly used, its effectiveness as a definitive treatment is debated.
  • This study retrospectively analyzed 24 patients who underwent laparoscopic cholecystectomy while hospitalized for such conditions between 2015 and 2019, revealing significant risks and complications associated with the procedure.
  • Results showed that laparoscopic cholecystectomy can be performed safely despite high-risk factors, with a notable incidence of complications (52%) and a 20.8% mortality rate, but it remains a viable treatment for those at risk for death from sepsis.

Article Abstract

Patients with cardiogenic shock (CS) or heart failure can develop ischemic cholecystitis from a systemic low-flow state. Cholecystectomy in high-risk patients is controversial. Percutaneous cholecystostomy tube (PCT) is often the chosen intervention; however, data on PCT as definitive treatment are conflicting. Data on cholecystectomy in these patients are limited. This study discusses outcomes following laparoscopic cholecystectomy (LC) in this patient population. This is a retrospective review of patients who underwent LC from 2015 to 2019 while hospitalized for CS or heart failure. Surgical services are provided by fellowship-trained minimally invasive surgeons at a single, academic, tertiary-care center. Patient characteristics are reported as frequencies' percentages for categorical variables. Odds ratio is used to determine the association between comorbidities and complications. Twenty-four patients underwent LC. Around 83% were white and 79% were male. Many were anticoagulated (88%), with Class IV heart failure (63%), and required vasopressors (46%) at the time of surgery. Fourteen of 24 (58%) had at least one circulatory device at the time of surgery: extracorporeal membrane oxygenation, left ventricular assist device, Impella, tandem heart, and total artificial heart. Four patients (17%) had PCT preoperatively. Fifteen days were the average interval between diagnosis and surgery. Pneumoperitoneum was tolerated by all, and 0% converted to open. Most common complication was bleeding (52%). Nine patients (37.5%) underwent 21 reoperations, one of which (4%) was related to cholecystectomy. Mortality occurred in 5 patients (20.8%); interval between cholecystectomy and mortality ranged 6-30 days. Although high risk, LC is a treatment option in patients with ischemic cholecystitis at risk for death from sepsis.

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Source
http://dx.doi.org/10.1089/lap.2024.0156DOI Listing

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