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The Human Skin Microbiome in Health: CME Part 1. | LitMetric

The Human Skin Microbiome in Health: CME Part 1.

J Am Acad Dermatol

Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

Published: August 2024

AI Article Synopsis

  • Human skin hosts various microorganisms, including bacteria and fungi, that help maintain skin health and balance.
  • Our knowledge of the skin microbiome is still developing, mostly from lab and animal studies, and more research is needed to apply these findings to humans.
  • The article explores the concept of the skin microbiome, its interactions with the host, and how changes to the microbiome can relate to skin diseases and potential treatments.

Article Abstract

Human skin is home to a myriad of microorganisms, including bacteria, viruses, fungi, and mites, many of which are considered commensal microbes that aid in maintaining the overall homeostasis or steady-state condition of the skin and contribute to skin health. Our understanding of the complexities of the skin's interaction with its microorganisms is evolving. This knowledge is based primarily on in vitro and animal studies, and more work is needed to understand how this knowledge relates to humans. Here, we introduce the concept of the skin microbiome and discuss skin microbial ecology, some intrinsic factors with potential influence on the human skin microbiome, and possible microbiome-host interactions. The second article of this two-part CME series describes how microbiome alterations may be associated with skin disease, how medications can affect the microbiome, and what microbiome-based therapies are under investigation.

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Source
http://dx.doi.org/10.1016/j.jaad.2024.07.1498DOI Listing

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