AI Article Synopsis

  • The study investigated the use of doxycycline injections as a treatment for persistent olecranon bursitis (OB) that didn’t respond to standard care, comparing it to surgical removal of the bursa.
  • Researchers analyzed data from 27 patients treated with doxycycline and 18 who underwent surgery over an 11-year period.
  • Results showed that doxycycline had a recurrence rate of 29.6% and high satisfaction levels (85.7%), while surgery had a lower recurrence rate of 16.7%, indicating that doxycycline may be a safe and effective non-surgical alternative for OB treatment.

Article Abstract

Purpose: This study aimed to determine the efficacy and safety of intrabursal injection of doxycycline sclerotherapy to treat olecranon bursitis (OB) refractory to conservative management.

Methods: We retrospectively reviewed 27 patients with recurrent OB who were treated over 11 years with intrabursal injections of doxycycline. They were compared with a control group of 18 patients with recurrent OB who underwent surgical bursectomy. Patients were re-evaluated by the treating physician for recurrence of bursitis and treatment complications and completed a questionnaire to assess satisfaction, pain, and other patient-reported outcomes.

Results: Eight patients (29.6%) undergoing doxycycline sclerotherapy had recurrence, requiring one more doxycycline lavage within the first 4 weeks of initial doxycycline treatment. Three patients (16.7%) undergoing surgery had recurrence after surgery, requiring repeat aspiration. There were no patients in either doxycycline or surgical groups with recurrence of bursitis at the final follow-up (median = 195 and 1,055 days, respectively). No patients in the doxycycline group ultimately required surgical bursectomy, and no patients undergoing surgery required repeat surgeries. A regression model controlling for covariates did not find a significant difference between groups in the likelihood of physician-identified complication or repeat aspiration after doxycycline lavage or surgical bursectomy. Of patients undergoing doxycycline sclerotherapy, 85.7% of patients reported high satisfaction (Likert score: 8-10), and 95.2% reported that they would pursue this treatment again.

Conclusions: Use of intrabursal doxycycline as a sclerosing agent for recurrent OB was safe and effective, with high patient satisfaction and no ultimate recurrence of bursitis at the final follow-up. This may be an effective alternative to surgical bursectomy for patients with recurrent OB refractory to conservative management.

Type Of Study/level Of Evidence: Therapeutic IV.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331157PMC
http://dx.doi.org/10.1016/j.jhsg.2024.03.006DOI Listing

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