AI Article Synopsis
- Molecularly imprinted polymers (MIPs) are specialized materials that act as “artificial receptors,” enabling the specific recognition of target molecules, and are increasingly used in biosensing applications.
- Researchers are focusing on improving the selectivity and sensitivity of MIPs by exploring new design methods, particularly concerning the choice of functional monomers that interact with various template molecules.
- The review highlights the significance of selecting appropriate functional monomers, discusses current challenges in the field, and emphasizes the importance of multiplex experiments and computer simulations for future advancements in molecular imprinting technology.
Article Abstract
Molecularly imprinted polymers, a type of special polymer materials, are widely used in biosensing and other fields due to their ability to specifically recognize target molecules, often called "artificial receptors.". Nowadays, researchers are constantly exploring new design and synthesis methods for molecularly imprinted materials to improve the selectivity and sensitivity of molecularly imprinted materials. Among them, the selection of functional monomers has attracted great attention. This review comprehensively analyzes and discusses the selection methods of functional monomers. The most commonly used functional monomers among different types of templates are screened based on the structural properties of the template molecules, including the selection of functional monomers among ion-imprinted polymers, protein-imprinted polymers, and bacterial imprinted polymers. The rich binding sites and functional group types of multifunctional monomers are also highlighted to advance the development of molecular imprinting technology. The article further explores the current challenges and prospects in the selection of functional monomers and emphasizes multiplex experiments and computer simulations as important directions for future research. This review provides comprehensive information and constructive guidelines for researchers in selecting functional monomers in areas such as analytical chemistry and biosensors.
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| http://dx.doi.org/10.1002/jssc.202400353 | DOI Listing |
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