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Effect of Preoperative Autologous Blood Storage in Major Hepatectomy for Perihilar Malignancy: A Randomized Controlled Trial.
Ann Surg
September 2024
Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Article Synopsis
- The study aimed to determine if preoperative autologous blood donation helps lower the risk of post-hepatectomy liver failure (PHLF) in patients with perihilar malignancy undergoing major liver surgery.
- Conducted as a randomized clinical trial, 138 patients were assigned to either receive autologous blood transfusions or not during their surgeries, with primary focus on post-operative PHLF rates.
- Results showed no significant differences in PHLF incidence or other surgery-related outcomes between the two groups, indicating that autologous blood storage did not effectively reduce PHLF risk.
Reappraisal of autologous stem cell transplantation for transformed indolent lymphoma in the bendamustine era.
Bone Marrow Transplant
November 2024
Alberta Health Services and University of Calgary, Calgary, AB, Canada.
Vitality of autologous retromolar bone grafts for alveolar ridge augmentation after a 3-months healing period: A prospective histomorphometrical analysis.
Clin Oral Implants Res
September 2024
Department of Oral- and Craniomaxillofacial Surgery/Translational Implantology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.
Objectives: The incorporation of retromolar bone grafts used for alveolar ridge augmentation is not well understood. This prospective observational study aims to supply histomorphometrical data from bone graft biopsies taken at the time of retrieval and after a 3-month healing period using patient-matched biopsies.
Materials And Methods: In 17 patients, trephine biopsies of the graft were acquired at the time of graft retrieval and after a 3-month healing period.
Obesity and the Latissimus Dorsi Flap: A Radiologic Study.
Plast Surg (Oakv)
May 2023
Division of Plastic Surgery, Department of Surgery, University of Louisville, KY, USA.
The increasing prevalence of obesity in patients with breast cancer has prompted a reappraisal of the role of the latissimus dorsi flap (LDF) in breast reconstruction. Although the reliability of this flap in obese patients is well-documented, it is unclear whether sufficient volume can be achieved through a purely autologous reconstruction (eg, extended harvest of the subfascial fat layer). Additionally, the traditional combined autologous and prosthetic approach (LDF + expander/implant) is subject to increased implant-related complication rates related to flap thickness in obese patients.
View Article and Find Full Text PDFImpact of autologous hematopoietic cell transplantation on disease burden quantified by next-generation sequencing in multiple myeloma treated with quadruplet therapy.
Am J Hematol
September 2022
Division of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
The incremental impact of autologous hematopoietic cell transplantation (AHCT) on disease burden with quadruplet induction in newly diagnosed multiple myeloma (NDDM) can be reappraised with the serial assessment of minimal residual disease (MRD). We describe the impact of AHCT on MM burden assessed by next-generation sequencing (NGS) for patients enrolled in a clinical trial utilizing quadruplet induction, AHCT, followed by MRD-adapted consolidation. We describe quantitative changes in MRD burden with AHCT and explore patient and disease features influencing the magnitude of MRD reduction with AHCT.
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