AI Article Synopsis
- Fracture-related infections are serious complications after surgery that lead to increased patient suffering and higher healthcare costs.
- Current tests for diagnosing these infections are inadequate, making early detection difficult.
- New research is focusing on advanced "omics" technologies and analytical methods to discover more reliable blood-based biomarkers for diagnosing these infections.
Article Abstract
Fracture-related infections are significant postoperative complications that carry substantial patient burden and additional healthcare costs. Despite their impact on outcome, early diagnosis of these infections remains challenging due to current available tests lacking acceptable diagnostic parameters. This review compiles existing information on blood-based biomarkers that have been evaluated as early diagnostic tools and highlights the challenges in their reliability. To begin to overcome these challenges new avenues of biomarker discovery utilizing "omics" technologies and novel analytical methods are being investigated in recent years. It appears that, despite their complexity, these newer approaches may be the future in biomarker discovery for fracture-related infection diagnosis.
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| http://dx.doi.org/10.1016/j.injury.2024.111823 | DOI Listing |
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