Objectives: To explore cancer survivors' historical and current use of analgesics for chronic chemotherapy-induced peripheral neuropathy (CIPN).
Sample & Setting: 142 post-treatment cancer survivors who received neurotoxic chemotherapy and were experiencing moderate to severe CIPN.
Methods & Variables: Participants completed the Treatment-Induced Neuropathy Assessment Scale at baseline and reported all analgesics used to manage CIPN. Frequency of historical or current prescription analgesic use for chronic CIPN was described and stratified by CIPN pain severity.
Results: At baseline, 31% of participants reported historical use of analgesics for CIPN and 46% of participants were currently using analgesics for CIPN. Gabapentin was the most frequently used analgesic, historically (20%) and currently (34%), and duloxetine was used less frequently (6% historical use, 10% current use). Many participants with severe pain (59%) reported using analgesics for CIPN.
Implications For Nursing: Duloxetine, the first-line treatment for chronic CIPN pain, was used less frequently than gabapentin, a common prescription analgesic for neuropathic pain. Further research is needed to determine strategies to promote the implementation of evidence-based CIPN treatments in clinical practice.
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http://dx.doi.org/10.1188/24.ONF.445-450 | DOI Listing |
Transplant Cell Ther
December 2024
Aflac Blood and Cancer Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA, USA.
Chronic graft versus host disease (cGVHD), occurs in approximately one in five pediatric allogeneic HCT patients and is a leading cause of late morbidity and mortality. Late effects of HCT may lead to long-term chronic health conditions and shortened life expectancy. In addition to direct physiological challenges from cGVHD and other late-effects, numerous patient-important outcomes impact the quality of life (QOL) of patients and their families.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
December 2024
Department of Microbiology, Krishna VishwaVidyapeeth( Krishna Institute of Medical Sciences Deemed to be University), Karad, Maharashtra, India.
Objective: The purpose of this research intended to determine the impact of an multi-component exercise program on body composition and physical, emotional and social well being (PWB, EWB,SWB) in breast cancer survivors (BCS). Methods: One hundred and thirty two eight women with BC were enrolled in this research based on inclusion and exclusion criteria and were randomized into group A and B. Group A received breast cancer (BC) support group therapy whereas group B received multi-component exercise program.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
December 2024
Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Thailand.
Objective: Aim of the study was to evaluate and compare the prevalence female sexual dysfunction (FSD) in cervical cancer (CC) survivors to a healthy female population.
Materials And Methods: This observational prospective trial was conducted at Thammasat University Hospital, Thailand, between April 2023 and February 2024. Participants were CC survival who attended an outpatient cancer clinic.
Asian Pac J Cancer Prev
December 2024
Department of Microbiology, Krishna VishwaVidyapeeth( Krishna Institute of Medical Sciences Deemed to be University), Karad, Maharashtra, India.
Background: Breast surgery, radiation, chemotherapy and modified radical mastectomy (MRM) may cause long-term side effects such as decreased muscle strength, pulmonary function, cardio-respiratory fitness (CRF), altered body fat distribution and poor sleep quality. These short- and long-term repercussions have an enormous effect on physical functioning in this population. The goal of this research was to determine the effect of a multi-component exercise program on functional performance in breast cancer survivors.
View Article and Find Full Text PDFRadiother Oncol
December 2024
Department of Oncology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address:
Background And Purpose: We lack population-based data on the use and effectiveness of phosphodiesterase- 5inhibitors (PDE-5Is) in post-radiotherapy long-term prostate cancer survivors (PCaSs). In this cross-sectional survey performed 9 years after curative radiotherapy we explored PDE-5I use and the drugs'effectiveness in 1,092 nine-year PCaSs responding to the sexual items of EPIC-26. The findings from PCaSs were compared to those from 2,847 age-similar men from the general population (Norms).
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