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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409221 | PMC |
| http://dx.doi.org/10.1021/acsabm.4c01057 | DOI Listing |
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Nanofibrous 3D scaffolds capable of individually controlled BMP and FGF release for the regulation of bone regeneration.
Acta Biomater
December 2024
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:
The current clinical applications of bone morphogenetic proteins (BMPs) are limited to only a few specific indications. Locally controlled delivery of combinations of growth factors can be a promising strategy to improve BMP-based bone repair. However, the success of this approach requires the development of an effective release system and the correct choice of growth factors capable of enhancing BMP activity.
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