Medullary Thyroid Carcinoma: A Unique Case Report.

Cureus

Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical Sciences, Saveetha University, Chennai, IND.

Published: July 2024

AI Article Synopsis

  • - Medullary thyroid carcinoma is a rare tumor originating from parafollicular C-cells, linked to hereditary syndromes like FMTC and MEN 2, or it can occur randomly.
  • - A case is reported involving a 50-year-old man diagnosed with the cancer after a neck mass was identified and examined through fine needle aspiration and histopathology.
  • - Key markers for diagnosis and monitoring include carcinoembryonic antigen (CEA) and calcitonin, highlighting the importance of early detection and treatment for better survival rates.

Article Abstract

Medullary thyroid carcinoma is a rare neuroendocrine tumor derived from parafollicular C-cells. It can be inherited as part of syndromes, such as familial medullary thyroid cancer (FMTC) and multiple endocrine neoplasia type 2 (MEN 2), or it can arise sporadically. We herein report a unique case of medullary thyroid carcinoma in a 50-year-old male who presented with a neck mass. Fine needle aspiration cytology (FNAC) of the thyroid and histopathological examination revealed a diagnosis of medullary thyroid carcinoma. Both carcinoembryonic antigen (CEA) and calcitonin are the key serum markers utilized in the diagnosis and monitoring of medullary thyroid cancer (MTC). Thorough evaluation, prompt identification, and efficient treatment constitute the pivotal measures for ensuring favorable survival outcomes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331271PMC
http://dx.doi.org/10.7759/cureus.64969DOI Listing

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