Enhanced oxidative stability of deuterated squalene: the impact of labelling extent on chemical resilience.

RSC Adv

Australian Nuclear Science and Technology Organisation, National Deuteration Facility New Illawarra Rd, Lucas Heights 2234 New South Wales Australia

Published: August 2024

AI Article Synopsis

  • - Deuteration, the process of replacing hydrogen atoms with deuterium, impacts the oxidative stability of squalene, an important ingredient in cosmetics and vaccine adjuvants.
  • - The study quantified how different levels of deuteration affect the formation of harmful peroxides that can clog pores (comedogenic peroxides).
  • - Results showed that even a low level of deuteration (19%) significantly reduced the formation of these peroxides, indicating its potential benefits for product stability.

Article Abstract

The extent to which deuteration affects the oxidative stability of squalene, a nutrient and a commonly-used ingredient in cosmetics and vaccine adjuvants, has been quantified as a function of the extent of labelling. The formation of comedogenic peroxides was inhibited by levels of overall deuteration as low as 19%.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331757PMC
http://dx.doi.org/10.1039/d4ra05543hDOI Listing

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