AI Article Synopsis
- - The study aimed to explore factors related to post-stroke depression (PSD) in patients after COVID-19 restrictions were eased, focusing on 947 stroke patients.
- - Results showed a 14.15% prevalence of PSD, with significant associations found between depression and factors like TSH levels, CRP, family history of stroke, migraine history, and shorter sleep duration.
- - The findings suggest that CRP, family stroke history, migraine, sleep duration, and TSH are independent risk factors for developing PSD as restrictions ease.
Article Abstract
Purpose: Research on post-stroke depression (PSD) following the lifting of coronavirus disease 2019 (COVID-19) restrictions remains sparse. This study aimed to investigate the factors associated with PSD after the easing of COVID-19 restriction measures.
Patients And Methods: This cross-sectional study was conducted with 947 stroke patients (cerebral hemorrhage and cerebral infarction) meeting the inclusion criteria. Participants completed a demographic questionnaire and the Patient Health Questionnaire-9 (PHQ-9). Additionally, data were collected on C-reactive protein (CRP), homocysteine (Hcy), modified Rankin Scale (mRS), stroke site, National Institutes of Health Stroke Scale (NIHSS), thyroid-stimulating hormone (TSH), and the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification. This study assessed correlations between these indices and PSD.
Results: Stroke patients with a PHQ-9 score ≥5 were identified as having PSD, with a prevalence rate of 14.15%. No significant correlation was found between previous COVID-19 infection and PSD. However, multiple regression analysis revealed associations between PSD and the following factors: TSH (OR: 0.87, 95% CI: 0.76-1), CRP levels (OR: 1.01, 95% CI: 1-1.02), family history of stroke (OR: 4.25, 95% CI: 1.66-10.88), migraine history (OR: 8.63, 95% CI: 2.49-29.85), and shorter sleep duration (OR: 0.6, 95% CI: 0.51-0.71) (all 0.05).
Conclusion: CRP, family history of stroke, migraine, sleep duration, and TSH are identified as independent risk factors for PSD following the lifting of COVID-19 restrictions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331147 | PMC |
| http://dx.doi.org/10.2147/IJGM.S472339 | DOI Listing |
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