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| http://dx.doi.org/10.1111/jocd.16539 | DOI Listing |
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Mechanical properties of a polylactic 3D-printed interim crown after thermocycling.
PLoS One
January 2025
Department of Advanced General Dentistry, College of Dentistry, Yonsei University, Seoul, Korea.
Polylactic acid (PLA) has garnered attention for use in interim dental restorations due to its biocompatibility, biodegradability, low cost, ease of fabrication, and moderate strength. However, its performance under intraoral conditions, particularly under heat and moisture, remains underexplored. This study evaluated the mechanical properties of PLA interim crowns compared with those of polymethylmethacrylate (PMMA) and bisphenol crowns under simulated intraoral conditions with thermocycling.
View Article and Find Full Text PDFEffects of polylactic acid microplastics on dissolved organic matter across soil types: Insights into molecular composition.
J Hazard Mater
January 2025
Guangdong Basic Research Center of Excellence for Ecological Security and Green Development, Guangdong Provincial Key Laboratory of Water Quality Improvement and Ecological Restoration for Watersheds, School of Ecology, Environment and Resources, Guangdong University of Technology, Guangzhou 510006, China; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China.
Increasing evidence has highlighted the effects of biodegradable microplastics (MPs) on soil organic matter (SOM), but the role of soil type and incubation time remains unclear. This study investigated the effects of polylactic acid microplastics (PLA-MPs) on the amount and molecular composition of dissolved organic matter (DOM) across three paddy soil types (Ferralsol, Alfisol, and Mollisol) and incubation times, revealing soil-specific patterns in DOM transformation: PLA-MPs reduced DOM content in Ferralsol and Alfisol by 29.3-68.
View Article and Find Full Text PDFDifferent effects of bio/non-degradable microplastics on sewage sludge compost performance: Focusing on antibiotic resistance genes, virulence factors and key metabolic functions.
J Hazard Mater
January 2025
Key Laboratory of Marine Geology and Metallogeny, First Institute of Oceanography, Ministry of Natural Resources (MNR), Qingdao 266061, China.
Microplastics (MP) have aroused increasing concern due to the negative environmental impact. However, the impact of bio/non-biodegradable MPs on the sludge composting process has not been thoroughly investigated. This study examined antibiotic resistance genes (ARGs), virulence factors (VFs), and microbial community functions in sludge compost with the application of polylactic acid (PLA) and polypropylene (PP), using metagenomic sequencing.
View Article and Find Full Text PDFCo-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments.
Drug Des Devel Ther
January 2025
Department of Pharmaceutical Analysis, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou, 350122, People's Republic of China.
Purpose: The incidence of malignant melanoma (MM) has risen over the past three decades, and despite advancements in treatment, there is still a need to improve treatment modalities. This study developed a promising strategy for tumor-targeted co-delivery of Dacarbazine (DTIC) and miRNA 34a-loaded PHRD micelles (Co-PHRD) for combination treatment of MM.
Methods: To construct the dual drug-loaded delivery system Co-PHRD, poly (L-arginine)-poly (L-histidine)-polylactic acid (PLA) was employed as a building block.
Ultrasound-triggered release of vancomycin from a novel spinal device: Antibiotic release and efficacy in vivo.
Int J Pharm
January 2025
Department of Radiology, Thomas Jefferson University, 132 S. 10(th) Street, Main 10(th) Floor, Philadelphia, PA 19107, USA.
Post-surgical spinal infection occurs in up to 20% of patients, despite aggressive peri-operative antibiotic treatments. To improve prophylaxis, we have designed and evaluated an ultrasound-activated prophylactic antibiotic release system to combat post-surgical bacterial survival. Polylactic acid (PLA) clips (1 cm) were 3D-printed with an interior reservoir (0.
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