This narrative review was planned to explore the efficacy of plasma-rich protein in musculoskeletal injuries, emphasising its impact on inflammatory markers, growth factors and the healing process. Musculoskeletal disorders pose a significant global health concern, with the plasmarich protein therapy emerging as a promising rehabilitative technique due to its potential to enhance healing. The therapy utilises the patients' cells to stimulate growth, repair tissues, and modulate inflammation, offering a shift towards patient-friendly, non-hospitalised treatment. Through the modulation of inflammatory phases, stimulation of proliferative phases, and enhancement of remodelling phases, the plasma-rich protein therapy contributes to the expedited healing of musculoskeletal injuries. Clinical evidence supports its efficacy in reducing recovery time and managing pain, underscoring its therapeutic potential in musculoskeletal rehabilitation.
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