AI Article Synopsis
- The study investigates the growing trend of detransitioning from medical gender reassignment, focusing on the proportion of patients who stop their hormonal treatment and the associated risk factors.
- A nationwide follow-up analysis of 1,359 individuals in Finland revealed that 7.9% discontinued hormonal therapy over an average of 8.5 years, with a higher risk noted in those who began treatment later (2013-2019).
- Findings suggest that as more individuals seek medical gender reassignment, the likelihood of discontinuation has increased, possibly due to lowered thresholds for initiating treatment, resulting in potentially unbalanced decision-making.
Article Abstract
Background: With increasing numbers of people seeking medical gender reassignment, the scientific community has become increasingly aware of the issue of detransitioning from social, hormonal or even surgical gender reassignment (GR). This study aimed to assess the proportion of patients who discontinued their established hormonal gender transition and the risk factors for discontinuation.
Methods: A nationwide register-based follow-up was conducted. Data were analysed via cross-tabulations with chi-square statistics and t tests/ANOVAs. Multivariate analyses were performed via Cox regression, which accounts for differences in follow-up times.
Results: Of the 1,359 subjects who had undergone hormonal GR in Finland from 1996 to 2019, 7.9% discontinued their established hormonal treatment during an average follow-up of 8.5 years. The risk for discontinuing hormonal GR was greater among later cohorts. The hazard ratio was 2.7 (95% confidence interval 1.1-6.1) among those who had accessed gender identity services from 2013 to 2019 compared with those who had come to contact from 1996 to 2005. Discontinuing also appeared to be emerging earlier among those who had entered the process in later years.
Conclusions: The risk of discontinuing established medical GR has increased alongside the increase in the number of patients seeking and proceeding to medical GR. The threshold to initiate medical GR may have lowered, resulting in a greater risk of unbalanced treatment decisions.
Trial Registration Number (trn): Not applicable (the paper does not present a clinical trial).
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11334601 | PMC |
| http://dx.doi.org/10.1186/s12888-024-06005-6 | DOI Listing |
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