A woman in her 70s presented with approximately 2 years of sudden-onset gait and cognitive problems. She had been diagnosed with normal pressure hydrocephalus (NPH) and underwent ventriculoperitoneal shunt (VPS) placement 1 year prior. Before VPS placement, brain imaging showed ventriculomegaly and chronic infarction of the right putamen and claustrum. A lumbar drain trial resulted in modest improvement of gait dysfunction. She underwent VPS placement for suspected NPH, but her symptoms remained unchanged. Examination revealed mild cognitive impairment, left-sided and lower body predominant parkinsonism, as well as disproportionately prominent postural instability. Gait analysis showed increased gait variability, reduced velocity and shortened step length bilaterally. Motor and gait abnormalities did not change after administration of levodopa. Her symptoms have remained stable for up to 52 months since symptom onset. We postulate that the infarction affecting the right putamen and claustrum could have led to a higher-level gait disorder mimicking NPH.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/bcr-2024-259957 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Functional magnetic resonance imaging has been used in many studies to explore the neural mechanism of acupuncture in patients with post-stroke motor dysfunction. Inconsistent results have been found in these studies, however. This activation likelihood estimation (ALE) meta-analysis was designed to quantitatively integrate changes in brain activity and the neurological effects of acupuncture on patients with motor dysfunction after stroke.
View Article and Find Full Text PDFExploring arterial anatomy of the internal capsule: an analysis of the deep vascular structures and related white matter pathways.
Neurosurg Rev
September 2024
Department of Neurosurgery, Istinye University, Istanbul, Turkey.
Background And Objectives: The internal capsule is supplied by perforators originating from the internal carotid artery, middle cerebral artery, anterior choroidal artery and anterior cerebral artery. The aim of this study is to examine the vascular anatomy of the internal capsule, along with its related white matter anatomy, in order to prevent potential risks and complications during surgical interventions.
Methods: Twenty injected hemispheres prepared according to the Klingler method were dissected.
Right putamen and claustrum infarction mimicking normal pressure hydrocephalus.
BMJ Case Rep
August 2024
Department of Neurology, University of Rochester, Rochester, New York, USA.
A woman in her 70s presented with approximately 2 years of sudden-onset gait and cognitive problems. She had been diagnosed with normal pressure hydrocephalus (NPH) and underwent ventriculoperitoneal shunt (VPS) placement 1 year prior. Before VPS placement, brain imaging showed ventriculomegaly and chronic infarction of the right putamen and claustrum.
View Article and Find Full Text PDFPattern of abnormalities on gray matter in patients with medial temporal lobe epilepsy and hippocampal sclerosis: An updated meta-analysis.
Clin Neurol Neurosurg
October 2024
Catholic University of Pernambuco, Recife, Brazil.
Article Synopsis
- * This study examined gray matter changes in patients with mesial temporal lobe epilepsy (MTLE) with HS, using advanced imaging techniques and comparing results with healthy control groups.
- * Significant gray matter loss was found in both hemispheres, with specific brain regions affected, which may provide future insights for diagnostics, treatments, and understanding the progression of MTLE.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!