An environmentally friendly electrochemical strategy for the synthesis of SCF-containing oxindoles was developed. This electrochemical transformation was accomplished through a cascade trifluoromethylthiolation/cyclization of -acrylamides with AgSCF, obviating the requirement for external oxidants. A variety of functional groups were well tolerated in this transformation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1021/acs.joc.4c00433 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!