AI Article Synopsis
- * Dysgeusia was experienced by 15% of patients, while the average weight loss during treatment was around 6%, with weight loss lasting for about half of the patients even after stopping the treatment.
- * To help minimize these side effects, researchers suggest that longer intervals between doses may be beneficial, indicating a need for further studies on this approach in future clinical trials.
Article Abstract
Talquetamab is an approved therapy for relapsed multiple myeloma. This study examined dysgeusia and weight loss occurrences, alongside investigating symptom reversibility post-treatment cessation. Dysgeusia was prevalent, persisting in 15% of patients. On average, patients lost 6% of their weight during treatment, with weight loss persisting in about half of the patients post-discontinuation. Weight loss and dysgeusia are important adverse events to consider while on talquetamab treatment. Extending dose intervals can potentially prevent such adverse events and should be studied in future prospective clinical trials.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327703 | PMC |
| http://dx.doi.org/10.1002/jha2.971 | DOI Listing |
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