A Rare Case of Emphysematous Osteomyelitis With Concurrent Septic Arthritis.

Cureus

Infectious Disease, Mount Carmel Health System, Grove City, USA.

Published: July 2024

AI Article Synopsis

  • Emphysematous osteomyelitis (EO) is a serious bone infection characterized by gas formation within the bones, often caused by anaerobic organisms, and is typically diagnosed via CT imaging.
  • A 76-year-old male presented with altered mental status and weakness, leading to the discovery of fluid and edema in his lumbar spine, raising suspicion for discitis or osteomyelitis.
  • A CT-guided biopsy confirmed the presence of gas in his vertebrae, and he was treated with intravenous ceftriaxone after cultures indicated susceptibility to antibiotics, while also developing a concurrent septic knee joint infection.

Article Abstract

A rare and possibly fatal infection of the bone called emphysematous osteomyelitis (EO) is caused by the presence of intraosseous gas due to gas-forming organisms. Common gas-producing organisms are in the family or are anaerobes. This gas within bones is most frequently detected using computed tomography (CT) imaging, and prompt diagnosis is important due to the high mortality rate. We present a 76-year-old male who complained of altered mental status, right upper and lower extremity weakness, and lower back pain. The MRI of the lumbar spine showed moderate edema in L3 and L4, with fluid in L3-L4 and L4-L5 concerning discitis/osteomyelitis. A CT-guided biopsy of L3/L4 was then performed by interventional radiology, revealing air present in the L3 and L4 vertebral bodies. Bone cultures from the L3 and L4 vertebra were later positive for that was susceptible to all tested antibiotics, and this was consistent with a diagnosis of vertebral EO. The infectious disease team recommended a six-week course of intravenous ceftriaxone. During the patient's hospital stay, he also developed a septic right knee joint positive for alongwith the concurrent vertebral EO.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330587PMC
http://dx.doi.org/10.7759/cureus.64898DOI Listing

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Article Synopsis
  • Emphysematous osteomyelitis (EO) is a rare and serious illness caused by bacteria that create gas, which can sometimes affect the spine and lead to intense back pain.
  • The article shares two cases of patients with advanced cancer who had this condition, illustrating how doctors diagnosed it using special imaging techniques like CT scans.
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Emphysematous osteomyelitis (EO) is a rare and severe bone infection characterized by the presence of gas within the bone and surrounding soft tissues, commonly caused by gas-forming bacteria. We present a case of an elderly patient with extensive EO due to  infection. The patient exhibited systemic signs of infection and severe localized pain.

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Background: Emphysematous osteomyelitis (EO) is a rare, rapidly progressing infection characterized by gas within bones, leading to severe morbidity if untreated. In the spine, EO can cause significant bone destruction and instability, requiring urgent surgical and medical intervention. Early diagnosis and a multidisciplinary approach are crucial for effective management and improved patient outcomes.

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