AI Article Synopsis

  • Thrombotic microangiopathy (TMA) refers to a range of conditions marked by blood clots in tiny blood vessels, leading to damage in organs.
  • Pregnancy-associated thrombotic microangiopathy (p-TMA) is a specific type of TMA that presents unique challenges in diagnosis and requires careful identification for proper treatment.
  • The review discusses different types of p-TMA, focusing on their underlying causes and the latest advancements in how to diagnose and manage them.

Article Abstract

Thrombotic microangiopathy (TMA) represents a heterogeneous group of disorders characterized by microvascular thrombosis and end-organ damage. Pregnancy-associated thrombotic microangiopathy (p-TMA) has emerged as a distinct clinical entity with unique diagnostic challenges. Identifying the specific form of p-TMA is critical for appropriate and timely management. This review offers a comprehensive overview of the various forms of thrombotic microangiopathies associated with pregnancy, highlighting our current understanding of their pathophysiology and the evolving landscape of diagnosis and treatment for each.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11328568PMC
http://dx.doi.org/10.1016/j.ekir.2024.05.016DOI Listing

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