J ISAKOS
Hospital for Special Surgery, Sports Medicine Institute, 535 East 70th Street, New York, NY, 10021, USA.
Published: October 2024
Objectives: The aim of this study is to evaluate the relationship between the achievement of clinically significant improvement in patient-reported outcome measures (PROMs) and the postoperative magnetic resonance image (MRI) appearance of matrix-associated chondrocyte implantation (MACI), in conjunction with patellofemoral realignment procedures, for the treatment of grade-IV chondral defects about the patellofemoral joint.
Methods: A retrospective review of patients undergoing MACI for grade-IV chondral defects of the patella or trochlea by a single sports-medicine-fellowship-trained surgeon from 2017 to 2020 was performed. Concomitant realignment procedures, including tibial tubercle osteotomy and medial patellofemoral ligament reconstruction, were also performed as needed. Patients with preoperative and minimum 1-year postoperative PROMs and postoperative knee MRI were included. MRI scans were obtained at 6.3 (interquartile range: 5.8, 7.5) months postoperatively. A fellowship-trained musculoskeletal radiologist assigned a Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score (range: 0-100, with 100 equating to complete graft healing) to each MRI. Achievement of the minimal clinically important difference (MCID) for International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Score-Quality of Life, and Kujala scores were determined for each patient. Paired t-tests or Wilcoxon rank-sum tests were used to evaluate for an association between achievement of the MCID for each PROM and MOCART score. The average follow-up time and time from surgery to PROMs were 2.7 ± 1.5 years and 1.7 ± 0.66 years, respectively.
Results: Thirty patients were included. There was a significant improvement in all PROMs from preoperative to postoperative (p < 0.001). More than two-thirds of patients achieved the MCID for each PROM. Patients who achieved the MCID for IKDC had significantly higher MOCART scores (66.5 ± 16.2) than those who did not meet the MCID for IKDC (50.6 ± 23.6, p = 0.043).
Conclusion: MACI for the treatment of patellofemoral chondral injuries is associated with clinically significant improvement in PROMs at short-term follow-up. Clinically significant improvements in IKDC scores are associated with a more mature MRI appearance of the autologous chondrocyte implantation graft on postoperative MRI, as indicated by higher MOCART scores.
Level Of Evidence: IV-Case Series.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jisako.2024.100311 | DOI Listing |
Zhongguo Gu Shang
January 2025
Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China.
Tibial plateau fracture is a fracture involving the proximal articular surface of the tibia, and its injury mechanism is complex, the fracture morphology is different, and it is often accompanied by different degrees of soft tissue injury, which is difficult to diagnose and treat. In recent years, the research hotspot has focused on solving the reduction and fixation of the posterior lateral column of the tibial plateau, because it has been clinically found that the residual sagittal plane after tibial plateau fracture is insufficient reduction or loss of reduction leads to knee joint dysfunction. The posterior inclination angle of the tibial plateau is an important parameter to describe the sagittal alignment of the tibia.
View Article and Find Full Text PDFJ ISAKOS
January 2025
Fowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada; Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar. Electronic address:
Introduction: This study aimed to assess the feasibility of using mobile application (app) technology for monitoring recovery after knee osteotomy and to determine the time required for patients to return to their preoperative step counts.
Methods: This retrospective study included 329 patients who underwent coronal realignment surgery, including high tibial osteotomy (HTO) or distal femoral osteotomy (DFO) with a minimum follow-up of 1 year. The patients were grouped based on the type of osteotomy performed, i.
J Orthop Res
January 2025
Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
The goal of medial open-wedge high tibial osteotomy (MOW-HTO) is to redistribute load by realigning the lower limb. This surgery is indicated for mild to moderate medial compartment osteoarthritis with varus deformity in cases unresponsive to conservative treatment. Procedures for accompanying cartilage lesions, such as multiple drilling on the medial femoral condyle (MFC), are often performed simultaneously, potentially affecting bone metabolism along with load redistribution and union progression.
View Article and Find Full Text PDFMagn Reson Med
January 2025
MR Physics, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Purpose: MR-based FID navigators (FIDnavs) do not require gradient pulses and are attractive for prospective motion correction (PMC) due to short acquisition times and high sampling rates. However, accuracy and precision are limited and depend on a separate calibration measurement. Besides FIDnavs, stationary NMR field probes are also capable of measuring local, motion-induced field changes.
View Article and Find Full Text PDFCurr Med Res Opin
January 2025
Investigator Initiated Study Promotion Center, Tokyo, Japan.
Objective: To explore the risk factors for discontinuation of pericapsular soft tissue and pelvic realignment (PSTP-R) therapy derived from Shiatsu in the candidates with osteoarthritis for total hip replacement (THR) (i.e., candidates for total hip replacement) treated from 2017 to 2020, and to identify the effect modifiers of PSTP-R therapy for patients who continued therapy for 6 months.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!
© LitMetric 2025. All rights reserved.