Objective: To compare perioperative opioid consumption in dogs undergoing pelvic limb surgeries and receiving a lumbosacral plexus block by combining a lumbar [lateral pre-iliac (LPI)] block with a lumbosacral trunk [i.e. parasacral (PS group) or greater ischiatic notch plane (GIN group)] block. Study design Retrospective, descriptive, exploratory, noninferiority cohort study.
Methods: Medical records of 37 client-owned dogs were analyzed. Intraoperative (primary outcome) and postoperative (24 hours) opioid use, 24 hour cumulative pain scores and prevalence of complications were compared between the two groups. Opioid use was quantified in morphine equivalents (ME, mg kg ). The noninferiority limit for intraoperative opioid consumption was set at 0.05 ME kg hour. Demographic data, procedure duration, surgery type and perioperative dexmedetomidine and ketamine use were also collected. A t-test or Wilcoxon rank-sum test, a Fisher's exact test and multivariable linear regression were used. Significance was set at p < 0.05.
Results: The GIN and PS groups comprised 17 and 20 dogs, respectively. Total intraoperative ME consumption was 0.17 (0.11-0.21) and 0.22 (0.16-0.30) mg kg hour for the GIN and PS groups, respectively (p = 0.077). The noninferiority analysis adjusted by surgery type and body mass revealed that the mean difference between the groups (GIN - PS) was -0.039 (95% CI -0.11-0.03, p = 0.247) ME mg kg hour, indicating that the GIN group was not inferior to the PS group regarding intraoperative ME consumption. Dexmedetomidine and ketamine use, postoperative ME consumption and pain scores were similar between groups.
Conclusions And Clinical Relevance: This retrospective study and preliminary observations support the clinical use of the GIN plane block, demonstrating its noninferiority to the PS block when combined with the LPI block for multimodal perioperative analgesia in dogs undergoing pelvic limb surgeries.
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http://dx.doi.org/10.1016/j.vaa.2024.07.008 | DOI Listing |
Cancer Immunol Immunother
January 2025
Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Histiocytic sarcoma (HS) is a rare yet lethal malignancy with no established standard of care therapies. A lack of pre-clinical models limits our understanding of HS pathogenesis and identification of therapeutic targets. Canine HS shares multiple clinical and genetic similarities with human HS, supporting its use as a unique translational model.
View Article and Find Full Text PDFJ Vet Sci
October 2024
Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Importance: Patients with arthritis and ruptured cruciate ligaments typically require surgery. Following surgery, it is necessary to improve joint function in early stage.
Objective: This study aimed to investigate the impact of intraoperative intra-articular injection of the ELHLD peptide (L-glutamyl-L-leucyl-L-histidyl-L-leucyl-L-aspartic acid) on postoperative stifle function in patients with medial patella luxation grade 3 and osteoarthritis grade 2 undergoing tibial plateau leveling osteotomy due to anterior cruciate ligament (ACL) rupture.
Front Vet Sci
December 2024
Department of Surgery, College of Veterinary Medicine, Jeonbuk National University, Iksan-si, Republic of Korea.
Introduction: Laparoscopic surgery is increasingly utilized for its minimally invasive nature, leading to reduced postoperative pain and faster recovery. This study aimed to compare postoperative pain, surgical complications, and recovery between laparoscopic-assisted ovariohysterectomy (LAOHE) and open ovariohysterectomy (OHE) in dogs.
Methods: A total of 40 healthy female dogs were randomly assigned to undergo either LAOHE ( = 20) or OHE ( = 20).
Am J Vet Res
January 2025
Telemedicine Department, IDEXX Laboratories, Westbrook, ME.
Objective: The investigators sought to reanalyze previously published vertebral heart size (VHS) reference intervals in Yorkshire Terriers (YTs), Pomeranians (POMs), Pugs, and Boston Terriers (BTs).
Methods: The electronic medical records of IDEXX Telemedicine Consultants were searched for YTs, POMs, Pugs, and BTs undergoing radiography between January 1, 2023, and March 31, 2023. Dogs were included if they had 2- or 3-view thoracic radiographs performed and no evidence of cardiopulmonary or systemic disease.
Open Vet J
November 2024
Animal Eye Care, Melbourne, Australia.
Background: Corneal squamous cell carcinoma (cSCC) is a rare neoplasm of dogs that can be treated with various modalities, principally by superficial keratectomy (SK) surgery. It is common to treat cSCC with multiple adjunctive therapies, but this may not always be practical for clinicians, clients, or patients.
Aim: This retrospective study describes the signalment of affected dogs, concurrent medical therapy, and success rate of surgical treatment of cSCC with SK surgery alone or in combination with adjunct therapy.
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