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Intensive Outreach for Mental Health: Young People's Experiences of an Intensive Outreach Model on Recovery and Engagement.
Community Ment Health J
January 2025
School of Psychology and Public Health, La Trobe University, Plenty Road & Kingsbury Drive, Bundoora, VIC, 3086, Australia.
Engagement with traditional mental health services can be particularly challenging for young people experiencing severe and complex mental health problems. Assertive community treatment-based services providing mobile outreach, such as Intensive Mobile Youth Outreach Services (IMYOS), operate across Australia to support these young people's mental health needs in the transition to adulthood. Past research on IMYOS has focused on quantitative outcome measures, and young people's experiences of this type of model are poorly understood.
View Article and Find Full Text PDFRole of TLR4 activation and signaling in bone remodeling, and afferent sprouting in serum transfer arthritis.
Arthritis Res Ther
December 2024
Department of Medicine, University of California, 9500 Gilman Dr. MC 0663, La Jolla, San Diego, CA, USA.
Background: In the murine K/BxN serum transfer rheumatoid arthritis (RA) model, tactile allodynia persists after resolution of inflammation in male and partially in female wild type (WT) mice, which is absent in Toll-like receptor (TLR)4 deficient animals. We assessed the role of TLR4 on allodynia, bone remodeling and afferent sprouting in this model of arthritis.
Methods: K/BxN sera were injected into male and female mice with conditional or stable TLR4 deletion and controls.
The epidemiology of notifiable diseases in Australia and the impact of the COVID-19 pandemic, 2012-2022.
BMC Glob Public Health
January 2024
School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.
Background: Infectious disease surveillance tracks disease epidemiology and informs prevention and control. Public health measures implemented in Australia during the COVID-19 pandemic (2020 to 2022) affected infectious disease epidemiology. We examined notifiable disease epidemiology in Australia from 2012 to 2022, evaluating disease trends and pandemic impacts.
View Article and Find Full Text PDFArtificial intelligence in respiratory care: perspectives on critical opportunities and challenges.
Breathe (Sheff)
October 2024
The University of Edinburgh, Allergy and Respiratory Research Group, Usher Institute, Edinburgh, UK.
Artificial intelligence (AI) is transforming respiratory healthcare through a wide range of deep learning and generative tools, and is increasingly integrated into both patients' lives and routine respiratory care. The implications of AI in respiratory care are vast and multifaceted, presenting both promises and uncertainties from the perspectives of clinicians, patients and society. Clinicians contemplate whether AI will streamline or complicate their daily tasks, while patients weigh the potential benefits of personalised self-management support against risks such as data privacy concerns and misinformation.
View Article and Find Full Text PDFEfficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial.
Lancet Respir Med
January 2025
Late-stage Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. Electronic address:
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