AI Article Synopsis
- * The research indicates that these agents not only enhance reproductive health under normal conditions but also help protect oocytes from damage caused by toxins, heat, and aging.
- * The findings suggest that adopting hormetic-based diets and lifestyles could boost reproductive success, applicable to both animal farming and human health, while expanding the understanding of hormesis in biological processes like fertilization and embryo development.
Article Abstract
The present paper provides the first integrative assessment of the capacity of dietary, endogenous and other agents to induce hormetic dose responses in oocytes, their supportive cells such as granulosa cells, blastocyst formation and early stage embryo development with the goal of improving fertility and reproductive success. The analysis showed that numerous agents enhance oocyte maturation and blastocyst/embryonic development in an hormetic fashion. These findings indicate that numerous agents improve oocyte-related biological functioning under normal conditions as well as enhancing its capacity to prevent damage from numerous chemical toxins and related stressor agents, including heat and age-related processes in pre-post conditioning and concurrent exposures. The present assessment suggests that hormetic-based lifestyles and dietary interventions may offer the potential to enhance healthy reproductive performance with applications to animal husbandry and human biology. The present findings also significantly extend the generality of the hormesis dose response concept to multiple fundamental biological processes (i.e., oocyte maturation, fertilization and blastocyst/embryo development).
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| http://dx.doi.org/10.1016/j.fct.2024.114941 | DOI Listing |
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