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Pediatric eosinophilic esophagitis: a Belgian single-center retrospective analysis reveals real-life difficulties in diagnosis and treatment.
Front Allergy
November 2024
Clinical Division of Pediatrics, University Hospitals Leuven, Leuven, Belgium.
Introduction: Eosinophilic esophagitis (EoE) is a chronic immune-mediated disorder characterized by eosinophilic infiltration of the esophageal mucosa.
Methods: This study aimed to provide insights into the clinical characteristics, diagnostic evaluation, treatment modalities, and outcomes of EoE in a pediatric population through a retrospective analysis of 79 patients followed in a single tertiary referral center between 2014 and 2020.
Results: As expected, a higher male prevalence was observed.
The Belgian IgE study: Staphylococcus aureus toxins in adult severe asthma.
J Allergy Clin Immunol Pract
November 2024
Medical Department, Novartis Pharma, Vilvoorde, Belgium.
Chronic spontaneous urticaria: Evidence of systemic microcirculatory changes.
Clin Transl Allergy
January 2024
Department of Immunology-Allergology, CHU Brugmann, Université Libre de Bruxelles (ULB), Laken, Belgium.
Background: Chronic spontaneous urticaria (CSU) is a chronic inflammatory skin disease where activation of endothelial cells (ECs) at sites of skin lesions leads to increased blood flow, leakage of fluid into the skin, cellular infiltration, and vascular remodeling. To understand the disease duration and the sometimes vague systemic symptoms accompanying flares, the objective of this study was to examine if CSU comes with systemic vascular changes at the microcirculatory level.
Methods: We investigated CSU patients (n = 49) and healthy controls (HCs, n = 44) for microcirculatory differences by nailfold videocapillaroscopy (NVC) and for blood levels of the soluble EC biomarkers serum vascular endothelial growth factor (VEGF), soluble E-selectin, and stem cell factor (SCF).
Epidemiology of sensitization to perennial aeroallergens in adults with severe asthma in Belgium. The BEIgE study.
Allergy
October 2023
Medical Department, Novartis Pharma, Vilvoorde, Belgium.
[New concept : The milk ladder, the climb to tolerance in non-IgE-mediated cow's milk protein allergy].
Rev Med Liege
April 2023
Centre pédiatrique d'Allergologie, CHC MontLégia, Liège, Belgique.
Cow's milk protein allergy (CMPA) is the leading cause of food allergy in young children. Despite the spontaneous acquisition of tolerance in the majority of cases at school age, the impact of CMPA on the quality of life of the child and his/her family is clearly more deleterious than in other food allergies. The milk scale, a form of oral immunotherapy, accelerates the acquisition of tolerance such as to curb this negative impact, through a process of gradually reintroducing milk into the diet of the allergic patient.
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