AI Article Synopsis
- The lymphatic system is a low-pressure fluid network that works alongside the circulatory system, helping maintain tissue fluid balance, transport immune cells, and absorb lipids.
- Recent research highlights the importance of cardiac lymphatic vessels, suggesting that promoting their growth (lymphangiogenesis) could help treat various cardiovascular diseases.
- The article reviews the development, functions, and interactions of cardiac lymphatics with conditions like atrial fibrillation and heart failure, while exploring potential therapies targeting these vessels for better cardiovascular health.
Article Abstract
The lymphatic system is the same reticular fluid system as the circulatory system found throughout the body in vascularized tissues. Lymphatic vessels are low-pressure, blind-ended tubular structures that play a crucial role in maintaining tissue fluid homeostasis, immune cell transport, and lipid absorption. The heart also has an extensive lymphatic network, and as research on cardiac lymphatics has progressed in recent years, more and more studies have found that cardiac lymphangiogenesis may ameliorate certain cardiovascular diseases, and therefore stimulation of cardiac lymphangiogenesis may be an important tool in the future treatment of cardiovascular diseases. This article briefly reviews the development and function of cardiac lymphatic vessels, the interaction of cardiac lymphatic vessels with cardiovascular diseases (including atrial fibrillation, coronary atherosclerosis, and heart failure), and finally discusses the therapeutic potential of targeted cardiac lymphatic therapy for cardiovascular diseases.
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| http://dx.doi.org/10.1097/CRD.0000000000000743 | DOI Listing |
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