Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/bjd/ljae328 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Laboratory Opossum () Is a Unique Model for Research on Zika Virus: Robust Immune Response, Widespread Dissemination, and Long-Term Persistence.
Viruses
November 2024
Division of Human Genetics, School of Medicine, The University of Texas Rio Grande Valley, Edinburg/Harlingen/Brownsville, McAllen, TX 78520, USA.
The Zika virus (ZIKV) epidemic elicited a rapid commitment to the development of animal models for ZIKV research. Non-human primates (NHPs) and mice have made significant contributions to this research, but NHPs are expensive, have a long gestation period, and are available only in small numbers; non-genetically modified mice are resistant to infection. To address these deficiencies, we have established the laboratory opossum, , as a small animal model that complements the mouse and monkey models.
View Article and Find Full Text PDFSerious infections and tuberculosis adversely impact outcomes of juvenile onset systemic lupus erythematosus in India.
Lupus
December 2024
Department of Clinical Immunology & Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Background: Infections are a major cause of morbidity and mortality in juvenile systemic lupus erythematosus (SLE). We assessed the incidence and risk factors for major infections in juvenile SLE.
Methods: A retrospective review of 225 patients of juvenile SLE (ACR 1997 criteria) with age <18 years visiting the rheumatology clinic at a single centre between 2000 to 2020 was done from case records and the hospital electronic health records.
A Rare Case of Juvenile Systemic Sclerosis With Concurrent Disseminated Tuberculosis: Diagnostic and Therapeutic Challenges.
Cureus
December 2024
Department of Pediatrics, Rajendra Institute of Medical Sciences, Ranchi, IND.
We present the case of a 13-year-old female diagnosed with juvenile systemic sclerosis, diffuse cutaneous subtype, along with active disseminated tuberculosis. This co-occurrence poses unique diagnostic and therapeutic challenges, particularly given the risk of tuberculosis exacerbation due to immunosuppressive therapy required for systemic sclerosis. The patient had signs/symptoms like progressive skin tightening and Raynaud's phenomenon; the diagnosis was confirmed by the presence of anti-Scl-70 antibodies.
View Article and Find Full Text PDFIncorporation of the central vein sign into the McDonald criteria.
Mult Scler Relat Disord
November 2024
Mellen Center for Multiple Sclerosis, Cleveland Clinic, Cleveland, United States. Electronic address:
Background: Diagnosis of multiple sclerosis (MS) frequently relies on MRI dissemination in time (DIT) and space (DIS), as codified in 2017 McDonald criteria (McD 2017). The central vein sign (CVS) is a proposed MS diagnostic biomarker, but its optimal incorporation into McD 2017 has not been extensively studied.
Objective: Evaluate the diagnostic performance of several methods incorporating CVS into McD 2017 radiological DIS criteria.
Is there a role of cytoreductive surgery with HIPEC in recurrent ovarian granulosa cell tumors? An Indian cancer center experience with review of literature.
Indian J Cancer
January 2024
Department of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Granulosa cell tumors (GCTs) are common ovarian tumors associated with a good prognosis but a tendency for late recurrences, making treatment difficult.
- A study evaluated the effects of cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) on eight patients with recurrent adult GCTs, showing a median overall survival of 11.5 months post-treatment.
- The procedure demonstrated acceptable levels of postoperative complications, but more research is needed to confirm its effectiveness as a treatment option for recurrent GCTs.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!