Understanding tendon mechanical properties, such as stiffness and hysteresis, can provide insights into injury mechanisms. This research addresses the inconsistency of previously reported and tendon hysteresis properties. Although limited, our preliminary findings suggest that hystereses (Mean ± SD; 55% ± 9%) are greater than hystereses (14% ± 1%) when directly comparing the same tendon for the same loading conditions in a sheep model within 24 h . Overall, it therefore appears that the tendon mechanical properties are affected by the testing environment, possibly related to differences in muscle-tendon interactions and fluid flow experienced . This communication advocates for more detailed investigations into the mechanisms resulting in the reported differences in tendon behaviour. Overall, such knowledge contributes to our understanding of tendon function towards improving modelling and clinical interventions, bridging the gap between and observations and enhancing the translational relevance of biomechanical studies.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11324601 | PMC |
http://dx.doi.org/10.3389/fphys.2024.1443675 | DOI Listing |
Heliyon
January 2025
Department of Orthopedics, Beijing LongFu Hospital, Beijing, China.
Objective: We aimed to investigate the effects of Tongluo Zhitong formula on synovial fibroblast proliferation in human knee osteoarthritis (KOA).
Methods: Discarded synovial tissue collected from patients undergoing total knee arthroplasty at our hospital was digested with type I collagenase. Primary culture was performed on three to four generations of fibroblasts, which were treated with high, medium, and low concentrations of Tongluo Zhitong formula.
Anat Cell Biol
January 2025
Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.
This review explores the novel perspective that the intermediate tendon of the digastric muscle may function as an anatomical trochlear pulley system within the human body, challenging the traditional understanding of trochlear systems. While widely recognized trochlear units include structures like the medial part of the humerus and the superior oblique muscle of the orbit, the review focuses on the unique anatomical arrangement of the intermediate tendon of the digastric muscle in connection with the anterior and posterior bellies of the digastric muscles. Despite current debates within the anatomical community about labeling the digastric muscles as having a trochlea, this paper delves into the scientific definition of a trochlear pulley system, presenting the intermediate tendon of the digastric muscle as a potential trochlea.
View Article and Find Full Text PDFPeerJ
January 2025
University of Amsterdam, Amsterdam, Netherlands.
Background: Achilles tendinopathy (AT) management can be difficult, given the paucity of effective treatment options and the degenerative nature of the condition. Innovative therapies for Achilles tendinopathy are therefore direly needed. New therapeutic developments predominantly begin with preclinical animal and in vitro studies to understand the effects at the molecular level and to evaluate toxicity.
View Article and Find Full Text PDFArthropod Struct Dev
January 2025
Zoological Museum, University of Kiel, Hegewischstrasse 3, 24105, Kiel, Germany.
The objective of this study is to gain a better understanding of the not well understood egg-transportation mechanisms through the female reproductive systems of crabs. For this, Carcinus maenas was chosen as a model to study the cuticular epithelium underlying the cuticle of the vagina and the ventral seminal receptacle. This cuticular epithelium is investigated by performing histochemical and ultrastructural analyses of the epithelial cells.
View Article and Find Full Text PDFActa Biomater
January 2025
Department of Biomedical Engineering, Lund University, Box 118, 221 00 Lund, Sweden.
While the number of studies investigating Achilles tendon pathologies has grown exponentially, more research is needed to gain a better understanding of the complex relation between its hierarchical structure, mechanical response, and failure. At the microscale, collagen fibers are, with some degree of dispersion, primarily aligned along the principal loading direction. However, during tension, rearrangements and reorientations of these fibers are believed to occur.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!